…Unlike verapamil and diltiazem, amlodipine has no clinically significant negative inotropic effect and can therefore be used in heart failure with reduced ejection fraction when…

…when an ACE inhibitor must be switched due to cough. The target dose in heart failure is 32 mg — four times the usual hypertension dose.

…in hypertensive crisis: onset is slow, duration 8–24 hours, and the effect varies widely between individuals because it is governed by plasma volume and…

…agonist without alpha or beta effects, with onset within minutes and duration under one hour — theoretically attractive in hypertensive crisis with renal involvement, but without…

…unsuitable as first-line treatment in hypertensive crisis — but useful in pre-eclampsia and as afterload relief in combination with a nitrate and beta-blocker.

…within minutes and duration under half an hour. A niche drug: catecholamine-induced hypertensive crisis — phaeochromocytoma, cocaine and amphetamine intoxication, MAO inhibitor crisis — and local…

Trandate Kombinerad α₁- och β-blockerare Arbetshästen vid hypertensiv kris i Sverige. Den kombinerade alfa- och betablockaden sänker trycket utan reflextakykardi, vilket gör preparatet användbart…

…men mer förlåtande. Ger relativt mer venodilatation än arteriolär dilatation jämfört med nitroprussid, och är ett förstahandsalternativ vid hypertensiv kris med graviditet eller cerebrovaskulär sjukdom.

…både vener och artärer — vendilatationen dominerar vid låga doser och sänker preload, artärdilatationen tillkommer vid högre doser. Förstahandsval vid hypertensiv kris med lungödem eller myokardischemi.

Salures Bendroflumetiazid Evolan Thiazide diuretic Inhibits the Na⁺/Cl⁻ cotransporter in the distal tubule and is the most commonly used thiazide diuretic for hypertension. The…

…tablet once daily for hypertension and stable angina. The selectivity for vascular smooth muscle means felodipine lacks the nodal effects of verapamil and diltiazem — no…