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Secondary Hypertension: When and How to Investigate

…in every patient with newly diagnosed or referred hypertension, with particular vigilance when the clinical history includes hypokalaemia. Endocrine disorders account for many secondary forms…

Corticosteroids: quick reference for dose equivalents and stress dosing

…crisis: hypotension that does not respond to fluid, abdominal pain, vomiting, fever, hyponatraemia, hyperkalaemia, hypoglycaemia. Give hydrocortisone and an isotonic crystalloid. Exact doses according to…

Resistant Hypertension: Evaluation and Treatment

…secondary hypertension, treatment related contributors, and excess cardiovascular risk. The European definition requires failure to reduce office systolic and diastolic blood pressure to below 140…

Arterial Hypertension: Definition, Diagnosis and Out-of-Office Measurement

…for an underlying secondary cause. Evaluation and physical examination Standardized office measurement Accurate technique is essential because inconsistent or incorrect measurement may lead to misclassification…

The Cardiac Electrical Axis: ECG Criteria, Definition, Clinical Implications

…on the provided context, the primary etiologies for axis deviations include: Causes of Right Axis Deviation: Pulmonary hypertension (primary or secondary) [9, 16] Severe pulmonary…

Risk Factor Modification: The Evidence Base for Primary Prevention

…international cohort evidence. Metabolic risk factors make a particularly large contribution to cardiovascular disease. Hypertension is a major component of this burden, followed by non…

Cardiac Rehabilitation After Myocardial Infarction

…multidisciplinary secondary prevention intervention for patients with cardiovascular disease, including those recovering from myocardial infarction. It extends beyond exercise training to incorporate individualized physical activity…

Primary Aldosteronism: Screening and Management

…form of secondary hypertension. Aldosterone acts principally through the mineralocorticoid receptor (MR). After entering target cells, it binds the MR, which translocates to the nucleus…

ACE Inhibitor Cough and Angioedema: Practical Management

…and can last for years. ACE Inhibitor Induced Angioedema Angioedema secondary to ACE inhibitor therapy occurs in approximately 1% of patients. It manifests as localized…

Heart Failure With Preserved Ejection Fraction: Diagnosis and Treatment

…worse outcomes. Pulmonary hypertension secondary to left heart disease may occur because elevated left sided filling pressures are transmitted to the pulmonary circulation. Persistent pulmonary…

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