…By inhibiting SGLT2, these drugs produce coupled sodium and glucose loss in approximately a 1:1 stoichiometric relationship. The resulting glucosuria and natriuresis reduce proximal…

…the more myocardium can be salvaged. Call the PCI service in parallel with drug treatment and transport planning [1,5]. Symptom duration Under 12 hours…

…to alteplase and is simpler to administer, since the whole dose is given as a bolus [1,2]. In a meta analysis of three phase…

…help matter more than a single measured value [2]. Level Plasma glucose Meaning : : : Level 1, alert value < 3.9 mmol/L but at least…

…of poisons. Stabilisation according to ABCDE, the plasma glucose, a blood gas and an ECG all come before complete identification of the substance. Treatment of…

…continued Red flags and pitfalls Stopping basal insulin in type 1 diabetes. The single most dangerous prescribing decision on a ward. Not prescribing glucose measurement…

…fibrinogen, plasminogen activator inhibitor 1, serum viscosity, asymmetric dimethylarginine, homocysteine, white blood cell count, proinflammatory cytokines and C reactive protein. Increased urinary albumin/creatinine ratio…

…body, cardiac myocytes use ATP (adenosine triphosphate) as the primary energy source. ATP is produced by metabolizing carbohydrates (glucose), fats or proteins, whichever is available…

…and care settings [2]. Practical first actions Do the following in parallel, not sequentially: 1. Check previous creatinine values and establish the time course. 2…

…acute phase protein Thyroid Test Reference : : TSH 0.4–4.0 mIU/L Free T4 12–22 pmol/L Free T3 3.1–6.8…