…whereas heterozygous carriers of an X linked condition may develop a phenotype later and require delayed or individualized assessment. Disease specific genetic architecture HCM is…

…oxidized phospholipids carried on the particle. Genetic and Mendelian randomization studies support a causal relationship between Lp(a) associated genetic variants and coronary artery disease…

…Individuals with established clinical ASCVD require LDL C lowering to reduce recurrent major cardiovascular events, including myocardial infarction, stroke, peripheral arterial disease events and mortality…

…for heart failure and arrhythmias. Family History of Sudden Cardiac Death (FHSCD) : A history of SCD in close relatives suggests a genetic predisposition to arrhythmias…

…hospitalizations and visits for heart failure without disease recognition in the 3 years preceding diagnosis is also a notable red flag [8]. Furthermore, intolerance to…

…Atherosclerotic disease appears more likely to develop in the arterial segment proximal to the bridge, particularly in older adults. Consequently, an adult with bridging and…

…artery disease (CAD). FH results from pathogenic variants affecting proteins in the hepatic LDL receptor pathway. Reduced cellular uptake and clearance of LDL leads to…

ECG Genetic and miscellaneous conditions J wave syndromes: early repolarization pattern, Brugada syndrome, hypercalcemia and hypothermia The J wave – also referred to as Osborn's…

…space. Note that tachycardia, pulmonary embolism and ischemia may also cause electrical alternans. PQ segment depression. Sinus tachycardia. Refer to Figure 1 . Figure 1. Electrical…

…clinical characteristics and ECG features of pericarditis will be discussed here. From a clinical point of view, clinicians must be able to separate pericarditis from…