…concentration of sodium, which affects the sodium calcium exchanger such that ultimately intracellular calcium concentration increases. This makes more calcium available to the contractile proteins…

…present with symptoms of digitalis toxicity, which manifests across multiple organ systems. Non cardiac symptoms include headache, nausea, vomiting, generalized malaise, and visual disturbances such…

…frequently in East Asian populations. VA can occur as part of a more generalized vasospastic syndrome with migraine or Raynaud phenomenon. Associations have also been…

…aims of treatment Convulsive status epilepticus in adults is present with: an ongoing generalised tonic clonic seizure lasting at least 5 minutes, or repeated generalised…

…is a clinical diagnosis. Treat as anaphylaxis in any of the following: 1. Acute onset of skin or mucosal symptoms , for example generalised urticaria, itching…

…import) product, and the diagnosis instead rests on antibody analysis (AChR antibodies in about 80 % of generalised and around half of ocular myasthenia, thereafter MuSK…

…often visual, auditory or tactile hallucinations with a relatively clear level of consciousness and preserved orientation 12 to 48 hours Withdrawal seizures, usually generalised tonic…

…to the next of kin. Active malignancy with a risk of transmission (an individual assessment; certain tumour types are not a bar). Untreated generalised infection…