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Atropine: Dosing in Bradycardia and Its Limitations

…hypothermia, and hyperkalemia. Clinical Presentation and Symptoms The clinical manifestation of bradycardia depends on the adequacy of cardiac output. Isolated sinus bradycardia that is unaccompanied…

Secondary Hypertension: When and How to Investigate

…is associated with a greater likelihood of cure. When to investigate General indications Patients with suggestive signs, symptoms, or medical histories should undergo appropriate screening…

Heart Failure with Reduced Ejection Fraction (HFrEF)

Cardiology Definition and terminology Heart failure (HF) is a complex clinical syndrome characterized by symptoms and signs resulting from structural or functional impairment of ventricular…

Management of bradycardia (bradyarrhythmia)

…healthy and diseased individuals. Asymptomatic bradycardia may lack prognostic significance or be physiological, particularly in athletes and young individuals. The severity of symptoms and presence…

Coronary Anatomy and Segmental Classification for the Clinician

…vulnerability and the risk of future plaque rupture. Anatomical severity versus functional significance The physiological effect of a coronary lesion depends on more than its…

Atrial fibrillation: ECG, classification, causes, risk factors & management

…is too often discovered first at hospital admission due to its complications (stroke, thromboembolism, heart failure, dyspnea). Most individuals, however, do experience symptoms and th

Ejection fraction (EF): Physiology, Measurement & Clinical Evaluation

…dimensions and often lower ejection fraction, as compared with non athletes. This is explained by the fact that the athlete's heart produces significantly larger…

Antianginal Therapy: Beta-Blockers, Calcium Channel Blockers, Nitrates, and Ranolazine

…CCS. General strategy For most patients, initial therapy consists of a beta blocker and/or a calcium channel blocker (CCB). If symptoms remain inadequately controlled…

De-escalation and Shortened Dual Antiplatelet Therapy in Patients at High Bleeding Risk

…than to replace the default 12 month regimen in the general ACS population. Clinical context and patient selection Acute coronary syndrome ACS includes ST segment…

Carotid Artery Disease: Screening, Medical Therapy and Revascularisation

…TIA) or stroke. The risk associated with asymptomatic disease depends substantially on stenosis severity and plaque characteristics. In the general population, the prevalence of asymptomatic…

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