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Familial and Genetic Screening in Premature Cardiovascular Disease

…medicine is the systematic assessment of relatives and other individuals who may carry an inherited predisposition to cardiovascular disease. It combines a structured family history…

Cardiovascular Risk in Inflammatory and Autoimmune Disease

…autoimmune disease. The greatest risks were reported with systemic sclerosis, Addison disease, SLE and type 1 diabetes. Traditional factors such as smoking, family history of…

Carotid Artery Disease: Screening, Medical Therapy and Revascularisation

…hypertension, hypercholesterolaemia, and sedentary behaviour; family history, particularly in the broader assessment of peripheral arterial and aortic disease; planned surgery, especially carotid endarterectomy (CEA), coronary…

Risk Factor Modification: The Evidence Base for Primary Prevention

…of health, air pollution, family history, ethnicity, and frailty. Primary prevention is complemented by population level interventions. Population strategies aim to shift risk across the…

Dilated Cardiomyopathy (DCM): Definition, Types, Diagnostics & Treatment

…idiopathic or genetic dilation of the left ventricle . Patients with DCM typically develop heart failure early in life and a family history of heart failure…

Abdominal Aortic Aneurysm: Screening and Surveillance

…Family history also increases risk, particularly among first degree relatives, with siblings appearing to be especially affected. The principal determinant of adverse outcome is aneurysm…

Approach to patients with chest pain: differential diagnoses, management & ECG

…The table below shows a systematic history taking in patients presenting with chest pain (chest discomfort) or other symptoms suggestive of the five conditions listed…

A Novel Familial Cardiac Arrhythmia Syndrome Identified Using ECG

…arrhythmias were observed in the fifth decade of life in several family members. Imaging studies did not reveal structural cardiac abnormalities, nor coronary artery disease…

Statin Intolerance and Statin-Associated Muscle Symptoms

…muscle disease or a personal or family history of muscle disorders Acute infection Renal or hepatic impairment Hypothyroidism Vitamin D deficiency Concomitant interacting medications The…

Primary Aldosteronism: Screening and Management

…or bilateral adrenal hyperplasia. A family history is therefore important, particularly in patients with early onset hypertension or premature cerebrovascular disease. PA is associated with…

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