11 träffar

DrugNon-selective β₁- and β₂-agonist without alpha effect
Isoprenaline

…vessels — completely without alpha effect. The result is that heart rate rises while systemic vascular resistance and diastolic blood pressure fall, so the drug raises…

DrugLinkosamid med proteinsynteshämmande effekt
🇸🇪 Clindamycin

…Två egenskaper motiverar preparatet: utmärkt penetration i ben, led och mjukdelar med nästan full biotillgänglighet peroralt, och en hämning av bakteriell proteinsyntes som stänger av…

DrugSelective dopamine-1 receptor agonist
Fenoldopam

Corlopam Selective dopamine-1 receptor agonist The only antihypertensive that increases renal perfusion while blood pressure falls. A selective D1 agonist without alpha or beta…

DrugKortverkande β₂-agonist (SABA)
🇸🇪 Salbutamol

…Airomir Buventol Easyhaler Salbutamol Teva Kortverkande β₂-agonist (SABA) Snabbaste sättet att öppna en trång luftväg — anslag inom minuter och full effekt inom en kvart…

DrugHigh-potency glucocorticoid with long duration
Betamethasone

…a full steroid dose without an injection, and the long biological duration means a single dose suffices. Potency is approximately 25 times that of hydrocortisone…

DrugSynthetic catecholamine, β₁-agonist (inotropy)
Dobutamine

…tone. Strong β₁ effect with marked β₂ effect means that stroke volume increases while systemic vascular resistance falls at low doses — good in the cold…

DrugSGLT2 inhibitor
Empagliflozin

…20 in EMPA-KIDNEY. The glucose-lowering effect diminishes as eGFR falls, but the cardiorenal effect persists — which is the entire point of the drug.

DrugGabapentinoid, ligand to the α2δ subunit of voltage-gated calcium channels
Gabapentin

…acid transporter in the gut, so bioavailability falls as the dose rises and the dose–concentration relationship is non-linear. Hence the wide dose range…

DrugSpecific antidote to dabigatran, humanised Fab fragment
Idarucizumab

…never lets go. The effect is immediate and complete: unbound dabigatran in plasma falls by over 99 per cent directly after the infusion. The specificity…

DrugSyntetiskt tyroideahormon (T4)
🇸🇪 Levothyroxine

…att patienten tar tabletten rätt. Ung och hjärtfrisk patient kan starta på full substitutionsdos omkring 1,6 μg/kg, medan äldre och patienter med…

DrugFyrfaktorkoncentrat med faktor II, VII, IX och X
🇸🇪 Prothrombin complex concentrate

…och förstahandsval när warfarineffekt måste hävas omedelbart. Full effekt inom tio minuter och i en volym som en blödande patient tål, till skillnad från plasma…