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The chain of survival in sudden cardiac arrest

CPR Time is the most critical factor for survival in cardiac arrest. Life saving interventions must be initiated momentarily to maximize the probability of survival…

Non-ST Elevation Acute Myocardial Infarction (NSTEMI) and Unstable Angina

…adhesion (mediated by von Willebrand factor and Glycoprotein Ib IX V), activation (via thromboxane A2 and ADP), and aggregation (via Glycoprotein IIb/IIIa cross linking…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…adhesion molecules, transmigrate into the intima via diapedesis, and differentiate into tissue macrophages under the influence of macrophage colony stimulating factor (M CSF) [4] . These…

Anticoagulation Strategies in Atrial Fibrillation

…triad: blood stasis, endothelial dysfunction, and hypercoagulability [1] [2] . Mechanical stasis in AF is most pronounced in the left atrial appendage (LAA). The LAA is…

Pulmonary Embolism (PE)

…Thrombi formed in the deep veins in the legs or pelvis can detach and flow via inferior vena cava to the right atrium and ventricle…

Assessment of diastolic function by echocardiography

…is derived by measuring flow velocities across the mitral valve using pulsed Doppler. Estimating left ventricular filling pressure via e' . Measurement of deceleration time (DT) …

Assessment of the pupillary reflex in cardiac arrest

…pupillary light reflex is controlled by a simple neural circuit: light signals travel from the retina via the optic nerve (CN II) to the midbrain…

Diagnosis and management of supraventricular and ventricular tachyarrhythmias: Narrow complex tachycardia & wide complex tachycardia

…expeditious management is warranted. Initial management includes assessing the patient's clinical status (symptoms, hemodynamics), ECG and risk factors (age, previous disease, medications, laboratory results…

Risk Factor Modification: The Evidence Base for Primary Prevention

…mortality in the cited international cohort evidence. Metabolic risk factors make a particularly large contribution to cardiovascular disease. Hypertension is a major component of this…

Chronic Kidney Disease as a Cardiovascular Risk Factor

… vascular risk factors require close attention 3b 30–45 mL/min/1.73 m² Proteinuria may be present High risk of progression 4 15–30…

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