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Non-ST Elevation Acute Myocardial Infarction (NSTEMI) and Unstable Angina

…initiating mechanism, the exposure of thrombogenic material triggers a rapid cascade of platelet adhesion (mediated by von Willebrand factor and Glycoprotein Ib IX V), activation…

Risk Factor Modification: The Evidence Base for Primary Prevention

…The lifetime burden of CVD is related to the number and severity of cardiovascular risk factors. Five modifiable factors—systolic blood pressure, non HDL cholesterol…

Chronic Kidney Disease as a Cardiovascular Risk Factor

…factors for CKD and CVD. Hypertension and renal disease are bidirectionally related: hypertension accelerates CKD progression, while impaired renal function further increases blood pressure. Non…

The chain of survival in sudden cardiac arrest

CPR Time is the most critical factor for survival in cardiac arrest. Life saving interventions must be initiated momentarily to maximize the probability of survival…

Hypertension: Initial Combination Therapy and Drug Selection

Cardiology Pharmacology & dosing Definition and Therapeutic Rationale Hypertension is a major risk factor for atherosclerotic cardiovascular disease and contributes to microvascular and macrovascular complications. It…

Stroke Prevention in Atrial Fibrillation: Choosing Anticoagulation

Arrhythmias and arrhythmology Pharmacology & dosing Definition and pathophysiology Atrial fibrillation (AF) is a major independent risk factor for thromboembolism, including ischaemic stroke. This risk applies…

Cardiac Rehabilitation After Myocardial Infarction

…disease, including those recovering from myocardial infarction. It extends beyond exercise training to incorporate individualized physical activity counselling, risk factor modification, nutritional care, education, psychosocial…

Obesity and Cardiovascular Disease: Assessment and Treatment

…accumulation of adipose tissue. It is an important cause of cardiovascular disease (CVD), cardiovascular risk factor clustering, disability and premature mortality. Cardiovascular conditions associated with…

Cardiac arrest in intoxication (poisoning)

…Currently, opioid overdose stands as a predominant etiological factor for cardiac arrest within this demographic on a global scale. Numerous substances possess the potential to…

Deceased donor organ donation

… warm ischaemic time is the limiting factor The time critical element The diagnosis and the donor care The time from withdrawal of treatment to circulatory…

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