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LDL Cholesterol Targets Across Cardiovascular Risk Categories

…at high or very high risk. Prolonged exposure to lower LDL C concentrations is associated with lower ASCVD risk. Atherogenic particle burden is not completely…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…conceptual framework Acute coronary occlusion is the abrupt or progressive reduction of coronary blood flow sufficient to produce myocardial ischaemia and, when prolonged or severe…

Alcohol withdrawal and delirium tremens: quick reference

…part via NMDA receptors. With prolonged alcohol exposure the nervous system adapts through reduced GABA mediated inhibition and increased glutamatergic activity. When the alcohol level…

ST-Elevation Myocardial Infarction Complicated by Cardiogenic Shock

…caused by cardiac insufficiency. Sustained hypoperfusion reduces oxygen and nutrient delivery and, when severe or prolonged, produces multiorgan dysfunction and death. In the setting of…

Cardiac arrest in intoxication (poisoning)

…Irrigate skin and eyes using saline solution (NaCl) if suspected of toxin exposure. Gastrointestinal lavage is infrequently employed due to aspiration risks and inconclusive evidence…

Smoking Cessation: Pharmacotherapy and Cardiovascular Benefit

…exposures are associated with continued or resumed smoking after the acute event and warrant particular attention. Cardiovascular benefits of cessation The principal benefits relevant to…

Chronic Coronary Syndrome: Diagnosis and Initial Evaluation

…Precipitating factors, including exertion, emotional stress, meals, or exposure to cold. Relieving factors, including rest or medication. Time of day and temporal pattern. Change in…

Vasospastic (Prinzmetal) Angina: Provocation Testing and Treatment

…spasm produces a reversible functional occlusion and usually causes transmural ischaemia. The resulting abnormalities in left ventricular function may lead to myocardial infarction, ventricular tachycardia…

Non-ST Elevation Acute Myocardial Infarction (NSTEMI) and Unstable Angina

Introduction to Coronary Atherosclerosis, Plaques, Atherothrombosis Coronary atherosclerosis is a chronic, progressive, and highly dynamic inflammatory disease of the arterial wall. It is characterized by…

Contrast-Associated Acute Kidney Injury: Risk Assessment and Prevention

Cardiology Nephrology Definition and terminology Contrast associated acute kidney injury is an acute deterioration in renal function occurring after exposure to iodinated contrast media, particularly…

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