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Cardiovascular Risk in Women: Sex-Specific Factors

…rehabilitation and are less likely to attain blood pressure treatment goals. Female specific and female predominant risk factors Risk assessment should include reproductive and pregnancy…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…proteins in the hepatic LDL receptor pathway. Reduced cellular uptake and clearance of LDL leads to increased circulating LDL C. The principal genetic mechanisms involve:…

Contrast-Associated Acute Kidney Injury: Risk Assessment and Prevention

…dysfunction, haemodynamic instability, anaemia and other nephrotoxic exposures may contribute to tubular injury, making attribution to contrast alone difficult. In patients with normal renal function…

LDL Cholesterol Targets Across Cardiovascular Risk Categories

…in addition to LDL and other apoB containing particles. Cardiovascular risk categories Primary prevention For adults aged 40–75 years without diabetes and with LDL…

🟠 Ticagrelor (Brilinta, Brilique)

…ritonavir, and atazanavir) can lead to a significant increase in exposure to ticagrelor. Dosage: Acute Coronary Syndromes Treatment with Ticagrelor should start with a loading…

Alcohol and Cardiovascular Disease

…Progressive dilation can subsequently impair left ventricular ejection fraction. Enlargement of the left ventricle predisposes to atrial and ventricular arrhythmias. In advanced alcohol related cardiomyopathy…

Smoking Cessation: Pharmacotherapy and Cardiovascular Benefit

…for smoking and anticipated barriers to cessation. Exposure to second hand smoke. Use of cannabis, electronic cigarettes or other inhaled products. Readiness to attempt cessation…

Anticoagulants: quick reference for dosing, renal adjustment and reversal

…as in the table above for rivaroxaban and edoxaban. Check every 6 months 15 30 Dabigatran contraindicated. The other DOACs are possible according to FASS…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…moderately stenosed. Plaque rupture Plaques prone to rupture characteristically contain a large lipid pool, numerous macrophages or foam cells, and a thin fibrous cap. Disruption…

Physics of myocardial perfusion imaging (SPECT, PET): Radiotracers, perfusion, blood flow and viability

…annihilate each other, producing two gamma photons emitted in opposite directions. PET scanners detect these gamma rays to construct images with high spatial and temporal…

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