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Cardiovascular Risk in Women: Sex-Specific Factors

…and are reflected in cardiovascular structure and function. Sociocultural factors contribute independently to differences in exposure to risk, access to care, clinical assessment and treatment…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…affecting approximately 1 in 250,000–350,000 individuals. The lifelong exposure to high LDL C is central to the disease burden. In untreated HeFH…

Contrast-Associated Acute Kidney Injury: Risk Assessment and Prevention

…from the combined effects of contrast exposure and other ischaemic or nephrotoxic stresses. The kidney is particularly vulnerable to toxic injury because of its high…

LDL Cholesterol Targets Across Cardiovascular Risk Categories

…at high or very high risk. Prolonged exposure to lower LDL C concentrations is associated with lower ASCVD risk. Atherogenic particle burden is not completely…

🟠 Ticagrelor (Brilinta, Brilique)

…ritonavir, and atazanavir) can lead to a significant increase in exposure to ticagrelor. Dosage: Acute Coronary Syndromes Treatment with Ticagrelor should start with a loading…

Alcohol and Cardiovascular Disease

…sex , and genetically influenced effects on the cardiovascular system. Acute exposure produces transient haemodynamic and myocardial effects, whereas sustained heavy consumption is associated with hypertension…

Smoking Cessation: Pharmacotherapy and Cardiovascular Benefit

…for smoking and anticipated barriers to cessation. Exposure to second hand smoke. Use of cannabis, electronic cigarettes or other inhaled products. Readiness to attempt cessation…

Anticoagulants: quick reference for dosing, renal adjustment and reversal

…rivaroxaban and edoxaban. Check every 6 months 15 30 Dabigatran contraindicated. The other DOACs are possible according to FASS, but the documentation is insufficient; check…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…exposes the lipid core and extracellular matrix to circulating blood. Tissue factor within the plaque and tissue factor bearing microparticles contribute to activation of coagulation…

Physics of myocardial perfusion imaging (SPECT, PET): Radiotracers, perfusion, blood flow and viability

…administration. Radiotracers with higher levels of redistribution can move from areas of higher concentration to regions with lower concentration, for reasons other than perfusion differences…

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