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Cardiovascular Risk in Women: Sex-Specific Factors

…are more prevalent in women. Chronic kidney disease and several other comorbidities also contribute to the disproportionate cardiovascular burden in women. Depression and anxiety are…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…affecting approximately 1 in 250,000–350,000 individuals. The lifelong exposure to high LDL C is central to the disease burden. In untreated HeFH…

Contrast-Associated Acute Kidney Injury: Risk Assessment and Prevention

…from the combined effects of contrast exposure and other ischaemic or nephrotoxic stresses. The kidney is particularly vulnerable to toxic injury because of its high…

LDL Cholesterol Targets Across Cardiovascular Risk Categories

…at high or very high risk. Prolonged exposure to lower LDL C concentrations is associated with lower ASCVD risk. Atherogenic particle burden is not completely…

🟠 Ticagrelor (Brilinta, Brilique)

…ritonavir, and atazanavir) can lead to a significant increase in exposure to ticagrelor. Dosage: Acute Coronary Syndromes Treatment with Ticagrelor should start with a loading…

Alcohol and Cardiovascular Disease

…sex , and genetically influenced effects on the cardiovascular system. Acute exposure produces transient haemodynamic and myocardial effects, whereas sustained heavy consumption is associated with hypertension…

Smoking Cessation: Pharmacotherapy and Cardiovascular Benefit

…for smoking and anticipated barriers to cessation. Exposure to second hand smoke. Use of cannabis, electronic cigarettes or other inhaled products. Readiness to attempt cessation…

Anticoagulants: quick reference for dosing, renal adjustment and reversal

…rivaroxaban and edoxaban. Check every 6 months 15 30 Dabigatran contraindicated. The other DOACs are possible according to FASS, but the documentation is insufficient; check…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…and infarction Definition and conceptual framework Acute coronary occlusion is the abrupt or progressive reduction of coronary blood flow sufficient to produce myocardial ischaemia and…

Physics of myocardial perfusion imaging (SPECT, PET): Radiotracers, perfusion, blood flow and viability

…collides with an electron, they annihilate each other, producing two gamma photons emitted in opposite directions. PET scanners detect these gamma rays to construct images…

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