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Anticoagulants: quick reference for dosing, renal adjustment and reversal

…higher target Doses in venous thromboembolism Treatment doses in deep vein thrombosis and pulmonary embolism differ from the atrial fibrillation doses and include an initial…

Pulmonary embolism: quick reference for risk stratification and treatment

…with gastrointestinal and urogenital tumours Marked renal failure Low molecular weight heparin with dose adjustment, or warfarin Subsegmental pulmonary embolism without deep vein thrombosis An…

Acute Limb Ischaemia: Recognition and Urgent Management

…venous Doppler signals Evidence of systemic disease or a potential embolic source Neurological assessment is central to triage. Sensory loss extending beyond the toes and…

Stent Thrombosis: Timing, Causes, Diagnosis, and Prevention

…thrombosis is approximately 1% during the first year after stenting, although the risk is higher after treatment of ST segment elevation myocardial infarction (STEMI) and…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…red thrombus. The size and persistence of the thrombus depend not only on plaque composition but also on circulating thrombotic and fibrinolytic factors. Plaque erosion…

Indications and contraindications for myocardial perfusion imaging

…failure Acute pulmonary embolism, pulmonary infarction, or deep vein thrombosis Acute myocarditis or pericarditis Acute aortic dissection Physical disability that precludes safe and adequate testing…

The Fourth Universal Definition of Myocardial Infarction: Types 1–5

…disruption of an atherosclerotic plaque through rupture or erosion. The relative contributions of plaque disease and thrombus vary considerably. Thrombotic material may embolize distally and…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

…Other mechanisms include thrombosis, embolism, vasculitis, fibromuscular dysplasia, arterial entrapment, cystic adventitial disease and trauma. Atherosclerotic PAD is a manifestation of systemic arterial disease rather…

Pulmonary Embolism (PE)

…in pulmonary embolism is up to 20%, and roughly 30% of patients with pulmonary embolism or deep vein thrombosis experience a second thrombotic event within…

Type 2 Myocardial Infarction: Mechanisms and Management

…smooth muscle cell dysfunction, and dysregulation of sympathetic innervation), coronary embolism, and spontaneous coronary artery dissection with or without intramural haematoma. Spontaneous coronary artery dissection…

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