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Myocardial Infarction with Non-Obstructive Coronary Arteries: Causes, Work-up and Management

…include: Plaque rupture or plaque erosion with thrombosis, despite the absence of an angiographically obstructive lesion Coronary embolism or thrombus Epicardial coronary vasospasm Coronary microvascular…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

…over 40 years of age, atherosclerosis is the predominant cause. Other mechanisms include thrombosis, embolism, vasculitis, fibromuscular dysplasia, arterial entrapment, cystic adventitial disease and trauma…

Stent Thrombosis: Timing, Causes, Diagnosis, and Prevention

…of the stent, stent diameter less than 3 mm, long stent length Large thrombotic burdens increase procedural risk because thrombus can fragment, embolize to other…

Acute Limb Ischaemia: Recognition and Urgent Management

…refill and venous filling Pulses proximal and distal to the suspected obstruction Arterial and venous Doppler signals Evidence of systemic disease or a potential embolic…

ST-Elevation Myocardial Infarction: Diagnosis and Electrocardiographic Criteria

…evidence of peripheral embolism, or an unexplained drop in arterial pressure. Silent or unrecognized infarction occurs more often in patients without antecedent angina and in…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…between myocardial oxygen supply and demand. In many cases, the initiating process is plaque disruption with thrombosis; other cases result from spasm, microvascular dysfunction, embolism…

Indications and contraindications for myocardial perfusion imaging

…failure Acute pulmonary embolism, pulmonary infarction, or deep vein thrombosis Acute myocarditis or pericarditis Acute aortic dissection Physical disability that precludes safe and adequate testing…

The Fourth Universal Definition of Myocardial Infarction: Types 1–5

…disruption of an atherosclerotic plaque through rupture or erosion. The relative contributions of plaque disease and thrombus vary considerably. Thrombotic material may embolize distally and…

Type 2 Myocardial Infarction: Mechanisms and Management

…smooth muscle cell dysfunction, and dysregulation of sympathetic innervation), coronary embolism, and spontaneous coronary artery dissection with or without intramural haematoma. Spontaneous coronary artery dissection…

Anticoagulants: quick reference for dosing, renal adjustment and reversal

…the bleeding risk of the procedure and by renal function. In markedly reduced renal function (dabigatran at eGFR <30 mL/min, the other DOACs at…

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