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Metabolic Syndrome: Definition and Clinical Significance

…asymmetric dimethylarginine, homocysteine, white blood cell count, proinflammatory cytokines and C reactive protein. Increased urinary albumin/creatinine ratio reflects altered endothelial and renal pathophysiology in…

Secondary Hypertension: When and How to Investigate

Cardiology Endocrinology & metabolism Definition and pathophysiology Secondary hypertension is elevated blood pressure attributable to a specific, identifiable underlying cause. It should be considered in every…

Arterial Hypertension: Definition, Diagnosis and Out-of-Office Measurement

…based approach because cardiovascular benefit from blood pressure reduction may also occur in selected people whose pressure is elevated but below the conventional hypertension threshold…

Resistant Hypertension: Evaluation and Treatment

…In clinical practice, the condition is identified primarily through persistently elevated blood pressure despite multidrug treatment rather than through specific symptoms. The clinical importance lies…

Blood Pressure Targets in Older and Frail Adults

…Ageing is associated with progressive increases in systolic blood pressure (SBP), while diastolic blood pressure (DBP) rises less steeply and may remain stable or decline…

Heart Failure With Preserved Ejection Fraction: Diagnosis and Treatment

…failure (HF) is a clinical syndrome in which the heart cannot deliver blood at a rate appropriate to tissue requirements unless filling pressures are elevated…

Hypertension: Initial Combination Therapy and Drug Selection

…In adults with elevated blood pressure, nonpharmacological management should be actively implemented. Adults with blood pressure ≥140/90 mmHg should receive both lifestyle and antihypertensive…

🟠 Mean arterial pressure (MAP) calculator

…and vascular resistance. Advantages of measuring MAP over systolic blood pressure While systolic blood pressure (SBP) indicates the maximum pressure during heart contraction, it does…

Microvascular Angina and INOCA: Diagnosis with CFR and IMR

…in up to 70% of patients undergoing invasive coronary angiography, while approximately 25% of these patients have documented ischaemia. Among patients referred for invasive angiography…

Right Ventricular Infarction: Recognition and Haemodynamic Management

…common in patients with inferoposterior left ventricular infarction, while infarction confined predominantly to the right ventricle is rare. The clinical spectrum extends from limited right…

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