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Risk Factor Modification: The Evidence Base for Primary Prevention

…prevent the emergence of risk factors. It includes maintenance of favourable blood pressure, body mass index, cholesterol and glucose levels, together with a low salt…

Metabolic Syndrome: Definition and Clinical Significance

…insulin resistance, dyslipidaemia, elevated blood pressure and impaired glucose regulation. Diagnosis is based on the coexistence of defined clinical and laboratory components; the diagnostic criteria…

Blood Pressure Targets in Older and Frail Adults

…observational studies have sometimes suggested that lower blood pressure may be harmful in significantly frail patients, especially when baseline blood pressure is not markedly elevated…

Secondary Hypertension: When and How to Investigate

Cardiology Endocrinology & metabolism Definition and pathophysiology Secondary hypertension is elevated blood pressure attributable to a specific, identifiable underlying cause. It should be considered in every…

Arterial Hypertension: Definition, Diagnosis and Out-of-Office Measurement

…is elevated but below the conventional hypertension threshold. The traditional diagnostic threshold of 140/90 mmHg derives from epidemiological observations associating pressures above this level…

Heart Failure With Preserved Ejection Fraction: Diagnosis and Treatment

…failure (HF) is a clinical syndrome in which the heart cannot deliver blood at a rate appropriate to tissue requirements unless filling pressures are elevated…

🟠 Hypertensive emergency (crisis) - Drugs, doses & management

…Hypertensive emergency is defined as significantly elevated blood pressure (systolic pressure ≥180 mmHg and/or diastolic pressure ≥120 mmHg) with concurrent signs of acute organ…

Hypertensive emergency (crisis)

…Hypertensive emergency is defined as significantly elevated blood pressure (systolic pressure ≥180 mmHg and/or diastolic pressure ≥120 mmHg) with concurrent signs of acute organ…

Diuretic Strategy and Decongestion in Heart Failure

…compartments. Heart failure is defined physiologically by the inability of the heart to provide blood flow appropriate to tissue requirements unless filling pressures are elevated…

Heart Failure with Reduced Ejection Fraction (HFrEF)

…cardiovascular societies, defines HF as a clinical syndrome corroborated by elevated natriuretic peptide levels and/or objective evidence of pulmonary or systemic congestion [3] . Within…

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