Adrenalin Stragen EpiPen Jext α- and β-agonist The only drug that reverses all components of anaphylaxis, and the cornerstone of cardiac arrest treatment. The…

…the drug raises rate but not pressure. Used where rate itself is the problem: bradycardia while awaiting pacing, bradycardia-dependent torsades de pointes, and electrical…

Jardiance Synjardy Glyxambi SGLT2 inhibitor A diabetes drug now used mostly for reasons other than glucose control. Empagliflozin reduced cardiovascular death in type 2 diabetes…

…and can therefore be used in heart failure with reduced ejection fraction when blood pressure or angina requires it. The slow onset makes the drug…

…within minutes and duration under half an hour. A niche drug: catecholamine-induced hypertensive crisis — phaeochromocytoma, cocaine and amphetamine intoxication, MAO inhibitor crisis — and local…

…80 % of absorbed drug is eliminated renally, so renal function governs treatment entirely. Dyspepsia affects one in ten patients and is the most common reason…

Procoralan Ivabradine Accord Selective If-channel inhibitor in the sinus node The only drug that reduces heart rate without affecting contractility, blood pressure, or conduction…

Ezetrol Atozet Inegy Selective cholesterol absorption inhibitor Inhibits intestinal cholesterol uptake via NPC1L1 and reduces LDL by an additional 20–25 % on top of a…

…onset and minimal anticholinergic burden. The drug has two entirely different dosing worlds: a few milligrams in acute psychotic agitation in younger patients, and tenths…

…arrives and resolves quickly, which is an advantage: the drug suits as-needed use and can be discontinued with rapid recovery of renal function and…

…and the first months require flare prophylaxis because falling urate levels themselves trigger attacks. Two features make this drug dangerous: the hypersensitivity syndrome and the…

…the entire explanation for why the drug is ineffective in infranodal block. The effect comes within one minute and fades over an hour or so…

…heparin, dalteparin is eliminated renally, so at eGFR below 30 ml/min the effect accumulates and the dose must be adjusted or the drug changed.

…with albuminuria, with or without diabetes. The dose is the same — 10 mg once daily — for all indications, making this drug unusually straightforward to manage.

…the drug unsuitable as first-line treatment in hypertensive crisis — but useful in pre-eclampsia and as afterload relief in combination with a nitrate and…

…and depends on noradrenergic and sodium-channel-mediated modulation, not on antidepressant action. What limits treatment is anticholinergic side effects, and what makes the drug…

…maintenance-and-reliever therapy in the same inhaler. The two regimens must never be confused — this is the most common prescribing error with this drug…

…Willebrand factor and factor VIII. Selectivity for the V2 receptor means it lacks the vasoconstrictive effect of vasopressin. The danger is not the drug itself…

GlucaGen HypoKit Glucagon Novo Nordisk Baqsimi Ogluo Pancreatic hormone, glycogenolytic agent and inotrope Two entirely different drugs in the same ampoule. In severe hypoglycaemia, 1…

…never a guarantee. The key practical distinction is between the three dose levels: analgesia, procedural sedation, and induction are different drugs in the same ampoule.

…in structurally normal hearts. The CAST trial showed increased mortality after myocardial infarction — that boundary remains the most important fact in the drug's history.