21 träffar

DrugSGLT2 inhibitor
Empagliflozin

Jardiance Synjardy Glyxambi SGLT2 inhibitor A diabetes drug now used mostly for reasons other than glucose control. Empagliflozin reduced cardiovascular death in type 2 diabetes…

Drugα- and β-agonist
Adrenaline

Adrenalin Stragen EpiPen Jext α- and β-agonist The only drug that reverses all components of anaphylaxis, and the cornerstone of cardiac arrest treatment. The…

DrugLong-acting dihydropyridine calcium channel blocker
Amlodipine

…and can therefore be used in heart failure with reduced ejection fraction when blood pressure or angina requires it. The slow onset makes the drug…

DrugSelective If-channel inhibitor in the sinus node
Ivabradine

Procoralan Ivabradine Accord Selective If-channel inhibitor in the sinus node The only drug that reduces heart rate without affecting contractility, blood pressure, or conduction…

DrugNon-selective α-adrenergic blocker
Phentolamine

…within minutes and duration under half an hour. A niche drug: catecholamine-induced hypertensive crisis — phaeochromocytoma, cocaine and amphetamine intoxication, MAO inhibitor crisis — and local…

DrugXanthine oxidase inhibitor
Allopurinol

…and the first months require flare prophylaxis because falling urate levels themselves trigger attacks. Two features make this drug dangerous: the hypersensitivity syndrome and the…

DrugMuscarinic receptor antagonist (vagolytic)
Atropine

…the entire explanation for why the drug is ineffective in infranodal block. The effect comes within one minute and fades over an hour or so…

DrugDirect thrombin inhibitor (factor IIa)
Dabigatran

…80 % of absorbed drug is eliminated renally, so renal function governs treatment entirely. Dyspepsia affects one in ten patients and is the most common reason…

DrugClass IC antiarrhythmic
Flecainide

…in structurally normal hearts. The CAST trial showed increased mortality after myocardial infarction — that boundary remains the most important fact in the drug's history.

DrugHigh-potency first-generation antipsychotic (butyrophenone)
Haloperidol

…onset and minimal anticholinergic burden. The drug has two entirely different dosing worlds: a few milligrams in acute psychotic agitation in younger patients, and tenths…

DrugDirect-acting arteriolar vasodilator
Hydralazine

…the drug unsuitable as first-line treatment in hypertensive crisis — but useful in pre-eclampsia and as afterload relief in combination with a nitrate and…

DrugNon-selective COX inhibitor, propionic acid derivative
Ibuprofen

…arrives and resolves quickly, which is an advantage: the drug suits as-needed use and can be discontinued with rapid recovery of renal function and…

DrugNon-selective β₁- and β₂-agonist without alpha effect
Isoprenaline

…the drug raises rate but not pressure. Used where rate itself is the problem: bradycardia while awaiting pacing, bradycardia-dependent torsades de pointes, and electrical…

DrugTricyclic antidepressant
Amitriptyline

…and depends on noradrenergic and sodium-channel-mediated modulation, not on antidepressant action. What limits treatment is anticholinergic side effects, and what makes the drug…

DrugInhaled corticosteroid in fixed combination with long-acting β₂-agonist
Budesonide/formoterol

…maintenance-and-reliever therapy in the same inhaler. The two regimens must never be confused — this is the most common prescribing error with this drug…

DrugLow molecular weight heparin
Dalteparin

…heparin, dalteparin is eliminated renally, so at eGFR below 30 ml/min the effect accumulates and the dose must be adjusted or the drug changed.

DrugSGLT2 inhibitor
Dapagliflozin

…with albuminuria, with or without diabetes. The dose is the same — 10 mg once daily — for all indications, making this drug unusually straightforward to manage.

DrugSynthetic vasopressin analogue (V2 agonist)
Desmopressin

…Willebrand factor and factor VIII. Selectivity for the V2 receptor means it lacks the vasoconstrictive effect of vasopressin. The danger is not the drug itself…

DrugSelective cholesterol absorption inhibitor
Ezetimibe

Ezetrol Atozet Inegy Selective cholesterol absorption inhibitor Inhibits intestinal cholesterol uptake via NPC1L1 and reduces LDL by an additional 20–25 % on top of a…

DrugPancreatic hormone, glycogenolytic agent and inotrope
Glucagon

GlucaGen HypoKit Glucagon Novo Nordisk Baqsimi Ogluo Pancreatic hormone, glycogenolytic agent and inotrope Two entirely different drugs in the same ampoule. In severe hypoglycaemia, 1…

DrugNMDA-receptor antagonist, dissociative anaesthetic
Ketamine

…never a guarantee. The key practical distinction is between the three dose levels: analgesia, procedural sedation, and induction are different drugs in the same ampoule.