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Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…over extensor tendons, are characteristic clinical manifestations of untreated FH and may develop when the disorder is not recognized early in life. Corneal arcus and…

Cardiac amyloidosis

…Cardiac Amyloidosis Definition and Pathophysiology Cardiac amyloidosis (CA) is a protein misfolding disorder characterized by the extracellular deposition of misfolded fibrillar proteins in the myocardium…

Primary Aldosteronism: Screening and Management

…hyperaldosteronism or Conn syndrome, comprises disorders in which aldosterone secretion is inappropriately increased, relatively autonomous from angiotensin II and plasma potassium, and resistant to suppression…

🟠 Aspirin (Acetylsalicylic acid)

…potentiate the hypoglycemic effect of sulfonylureas, possibly due to reduced binding to serum albumin. Nicotinic acid: Acetylsalicylic acid may increase plasma levels of nicotinic acid…

ECG changes due to electrolyte imbalance (disorder)

…the severity of electrolyte imbalance and the visible ECG changes. Specific electrolyte disorders 1. Sodium Increased (hypernatremia) and decreased (hyponatremia) sodium levels do not have…

Hypoglycaemia: quick reference for emergency management

…low plasma glucose during the symptoms. 3. Resolution of the symptoms when the glucose is normalised [3]. A healthy person without diabetes therefore does not…

Hyponatraemia: quick reference for work-up and correction

…Hyponatraemia is primarily a disorder of water balance. The plasma sodium reflects the ratio between the body's exchangeable sodium and potassium and the total…

Preeclampsia and Hypertensive Pregnancy Disorders as Future Cardiovascular Risk

…antenatal hypertensive disorders, but it may also arise de novo after delivery. New onset postpartum preeclampsia is increasingly recognized as a significant cause of maternal…

Assessment of Pacemaker Malfunction

…include electrolyte disorders, metabolic disorders, hypoxemia, antiarrhythmic drugs, or electromagnetic disturbance caused by other machines/devices. Below follows ECG tracings demonstrating each type of failure…

The Fourth Universal Definition of Myocardial Infarction: Types 1–5

…cTn alone does not establish MI, because myocardial injury may occur without myocardial ischaemia. Non ischaemic myocardial injury may accompany numerous cardiac and systemic disorders…

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