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A Novel Familial Cardiac Arrhythmia Syndrome Identified Using ECG

…observed in the fifth decade of life in several family members. Imaging studies did not reveal structural cardiac abnormalities, nor coronary artery disease. Another male…

Familial and Genetic Screening in Premature Cardiovascular Disease

…selected congenital heart diseases, pulmonary arterial hypertension and thromboembolic disorders. Most recognised heritable cardiovascular conditions demonstrate autosomal dominant transmission, in which an affected heterozygous individual…

Ventricular fibrillation, pulseless electrical activity and sudden cardiac arrest

…Electrolyte disorders, acidosis, hypoxemia and ischemia all aggravate the risk of developing ventricular fibrillation, in any situation. ECG features of ventricular fibrillation The ECG shows…

The Fourth Universal Definition of Myocardial Infarction: Types 1–5

…Identification of a coronary thrombus by angiography or autopsy, except in type 2 and type 3 MI. A diagnosis of MI should not be made…

Cardiovascular Risk in Women: Sex-Specific Factors

…of cardiovascular disease. The biological differences between females and males arise partly from the chromosomal distinction between XX and XY individuals and are reflected in…

Primary Aldosteronism: Screening and Management

…absent in most diagnosed patients. Reliance on hypokalaemia alone therefore misses a substantial proportion of cases. The cardiorenal and cerebrovascular consequences of unrecognized PA make…

Vasovagal Syncope: Diagnosis, Tilt Testing and Treatment

…30% of males due to a lack of effective reflex response to posture, venous pooling, or external stimuli. The underlying pathophysiology is rooted in autonomic…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…over extensor tendons, are characteristic clinical manifestations of untreated FH and may develop when the disorder is not recognized early in life. Corneal arcus and…

Alcohol withdrawal and delirium tremens: quick reference

…use disorder and planned follow up , not merely detoxification. Benzodiazepines reduce the severity of withdrawal and the risk of seizures and delirium [1,2]. In…

ECG J wave syndromes: hypothermia, early repolarization, hypercalcemia & Brugada syndrome

…The T wave is negative (inverted). Early repolarization pattern Early repolarization occurs in 5% to 10% of all males. It is less common among women …

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