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Cardiac amyloidosis

…Despite congestive heart failure, a third or fourth heart sound is rarely heard due to restrictive pathophysiology and impaired ventricular relaxation [10]. There is also…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

…hypertension, diabetes mellitus and other adverse influences disturb these functions. The resulting endothelial dysfunction promotes inappropriate vasoconstriction, adhesion of circulating cells, inflammatory cell entry into…

Spontaneous Coronary Artery Dissection

…coronary disorder caused by separation within the coronary arterial wall, usually through formation of an intramural haematoma that compresses the true lumen. The resulting reduction…

Heart Failure with Reduced Ejection Fraction (HFrEF)

…failure (HF) is a complex clinical syndrome characterized by symptoms and signs resulting from structural or functional impairment of ventricular filling or ejection of blood…

Cardiovascular Risk in Women: Sex-Specific Factors

…conventional risk factors have sex dependent effects: Blood pressure rises more steeply in women from young adulthood, resulting in a greater lifetime burden of hypertension…

ST-Elevation Myocardial Infarction: Diagnosis and Electrocardiographic Criteria

…mistaken impression of indigestion. STEMI pain can simulate pain from acute pericarditis, pulmonary embolism, acute aortic dissection, costochondritis, and gastrointestinal disorders. Radiation of discomfort to…

Chronic Heart Failure With Reduced Ejection Fraction: Four-Pillar Therapy

…sleep disordered breathing, cancer related disease and cardiac amyloidosis among the relevant clinical settings or comorbidities. HFrEF is distinguished from heart failure with mildly reduced…

Assessment of Pacemaker Malfunction

…by the lead in the other chamber, resulting in inappropriate inhibition of the pacemaker in the latter chamber. This type of oversensing is referred to…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

…medicine Definition and pathophysiology Peripheral artery disease (PAD) is a clinical disorder caused by stenosis or occlusion of the aorta or arteries supplying the limbs…

Microvascular Angina and INOCA: Diagnosis with CFR and IMR

…MVA) is myocardial ischaemia caused by structural or functional abnormalities of the coronary microcirculation. These abnormalities may impair coronary flow reserve (CFR), reduce microcirculatory conductance…

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