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The Fourth Universal Definition of Myocardial Infarction: Types 1–5

…myocardial injury may accompany numerous cardiac and systemic disorders, including: Cardiac causes Systemic causes Heart failure Sepsis Myocarditis Chronic kidney disease Cardiomyopathy Stroke or subarachnoid…

Primary Aldosteronism: Screening and Management

…which translocates to the nucleus and induces expression of aldosterone responsive genes. Although the kidney is a major target—where MR activation promotes sodium transport…

Cardiovascular Risk Assessment with SCORE2 and SCORE2-OP

…adults with elevated blood pressure (BP), in whom absolute cardiovascular risk varies considerably according to age and the presence of concomitant risk factors. In contrast…

Cardiovascular Risk in Women: Sex-Specific Factors

…reproductive and pregnancy related history. Female specific or female predominant factors associated with later cardiovascular risk include: Premature menopause Premature ovarian insufficiency Hypertensive disorders of…

🟠 Aspirin (Acetylsalicylic acid)

…to moderate heart failure, kidney or liver disease, especially when combined with diuretics (risk of fluid retention and impaired kidney function). Patients with bronchial asthma…

Chronic Heart Failure With Reduced Ejection Fraction: Four-Pillar Therapy

…thyroid disease, iron deficiency and anaemia, kidney dysfunction, sleep disordered breathing, cancer related disease and cardiac amyloidosis among the relevant clinical settings or comorbidities. HFrEF…

Differential Diagnosis of Chest Pain: A Clinical Overview

…autoimmune disorder or known malignancy may suggest specific, nonidiopathic etiologies [2]. Summary of Pain Characteristics The following table synthesizes the key differential diagnoses and their…

ECG changes due to electrolyte imbalance (disorder)

…is a correlation between the severity of electrolyte imbalance and the visible ECG changes. Specific electrolyte disorders 1. Sodium Increased (hypernatremia) and decreased (hyponatremia) sodium…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

Cardiology Clinical medicine Definition and pathophysiology Peripheral artery disease (PAD) is a clinical disorder caused by stenosis or occlusion of the aorta or arteries supplying…

Vasovagal Syncope: Diagnosis, Tilt Testing and Treatment

…form of neurally mediated syncope (NMS), a disorder of autonomic reflexes. It typically occurs after attaining an upright posture or following painful stimuli and emotional…

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