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The physiology of cardiopulmonary resuscitation (CPR)

…in perfusion of cardiac, cerebral, and pulmonary tissue. Chest compressions produce perfusion of vital organs by increasing the pressure in the atria, ventricles and large…

Assessment of the pupillary reflex in cardiac arrest

…bilateral pupillary constriction (a brisk reflex), whereas low light causes dilation. This reflex is highly sensitive to brainstem integrity and cerebral perfusion. During cardiac arrest…

Hypertensive crisis: drugs and doses

…reference to the intravenous antihypertensive drugs used in a hypertensive emergency. It summarises the mechanism of action, the onset, the duration of effect, the dosing…

Terminology of sudden cardiac arrest and resuscitation

…cerebral perfusion and brain damage progresses rapidly. Low flow : The circulation (perfusion) achieved by performing CPR. Low flow time : The duration (minutes) from start of…

Short and long-term prognostication in cardiac arrest

…regardless of etiology, if the initial rhythm is asystole or PEA. Most current protocols for ECMO exclude patients presenting with asystole or PEA. Duration of…

🟠 Nitroglycerin

…μg/min. Time to onset of action: 2 to 5 minutes Duration of action: 5 to 10 minutes. Adverse effects Headache (cerebral vasodilation). Tachycardia …

Hyponatraemia: quick reference for work-up and correction

…cerebral oedema but makes the brain sensitive to a rapid increase in extracellular tonicity. This explains why acute hyponatraemia chiefly carries a risk of cerebral…

🟠 Nitroprusside

…dependent reduction in coronary and renal perfusion. • Dose dependent elevation of intracranial pressure (ICP) and reduction in cerebral blood flow. Caution • Used cautiously in patients…

Atrial Fibrillation in the Critically Ill Patient

…Subclinical cerebral injury may contribute to vascular dementia, and thromboembolism may affect organs other than the brain. Patients with AF in the setting of ACS…

Dilated Cardiomyopathy (DCM): Definition, Types, Diagnostics & Treatment

…Dilated cardiomyopathy (DCM) is defined as dilation of one or both ventricles. Dilation of the left ventricle is virtually always accompanied by impaired left ventricular…

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