Cardiology Endocrinology & metabolism Definition and Pathophysiology Type 2 diabetes mellitus (T2DM) is a major cardiovascular risk condition. It is associated with a two to four…

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…shift. For decades, the management of type 2 diabetes mellitus (T2DM) and obesity was siloed, with clinicians focusing primarily on hemoglobin A1c (HbA1c) reduction, blood…

…or more major epicardial coronary arteries. It frequently coexists with left main coronary artery disease, diabetes mellitus, left ventricular dysfunction, peripheral vascular disease and other…

…pharmacological basis Sodium glucose cotransporter 2 (SGLT2) inhibitors are a class of oral agents initially developed for glucose lowering in type 2 diabetes mellitus (T2DM)…

…Dyslipidaemia, cigarette smoking, hypertension, diabetes mellitus and other adverse influences disturb these functions. The resulting endothelial dysfunction promotes inappropriate vasoconstriction, adhesion of circulating cells, inflammatory…

…dyslipidaemia, and diabetes mellitus Reduce anxiety and depressive symptoms Facilitate return to work and appropriate recreational or sporting activity Limit recurrent myocardial infarction, cardiovascular morbidity…

…considered at increased cardiovascular risk without a calculated SCORE2 or SCORE2 OP estimate when certain clinical conditions are present. These include diabetes mellitus, familial hypercholesterolaemia…

…more likely with: Small reference vessel diameter A small post procedural lumen Substantial residual stenosis Long lesions Diabetes mellitus Untreated edge dissection Components and mechanisms…

…thrombosis for clinical research and outcome assessment. Predisposing factors Domain Factors associated with stent thrombosis Clinical Acute myocardial infarction, diabetes mellitus, renal failure, heart failure…