Fragmin Low molecular weight heparin The workhorse anticoagulant in hospital practice: subcutaneous dosing once daily, predictable effect, and no need for routine monitoring, allowing home…

Zyrlex Cetirizin Sandoz Cetirizin Teva Second-generation H₁-antihistamine First-line treatment for allergic rhinoconjunctivitis and chronic urticaria — one tablet daily, available without prescription, with…

…thromboxane synthesis in platelets for their entire lifespan. This is why a low once-daily dose is sufficient, and why the effect persists for 7…

…cornerstone drug for hypertension and stable angina, and the easiest calcium channel blocker to use: once-daily dosing, a half-life of almost two days…

…hydrolysed to candesartan during absorption that binds the AT₁-receptor tightly and slowly reversibly — hence the even effect over 24 hours with once-daily dosing…

…and Borrelia. Near-complete oral absorption and a long half-life make once-daily dosing possible. It is the standard choice in pneumonia in penicillin…

…Logimax Vascular-selective dihydropyridine calcium channel blocker A highly vascular-selective dihydropyridine given as a modified-release tablet once daily for hypertension and stable angina…

…which is the entire point in adrenocortical insufficiency — and the short duration allows the daily dose to be distributed to mimic the physiological cortisol pattern…

…per cent of the body's total potassium store — the plasma value indicates the starting point, not the magnitude of the deficit. Rate, not daily…

…effect relationship without the CYP2D6-dependent variability that makes metoprolol response unpredictable. The half-life of 10–12 hours is sufficient for once-daily dosing.

…with albuminuria, with or without diabetes. The dose is the same — 10 mg once daily — for all indications, making this drug unusually straightforward to manage.

…and the dose–concentration relationship is non-linear. Hence the wide dose range and three-times-daily regimen. Used in peripheral neuropathic pain and as…