Cardiology Endocrinology & metabolism Definition and Pathophysiology Metabolic syndrome is a clustering of cardiometabolic abnormalities centred on abdominal adiposity, insulin resistance, dyslipidaemia, elevated blood pressure and…

…Endothelial dysfunction may contribute to both microvascular and epicardial vasomotor disorders. Endothelial activation can promote the release of adhesion molecules, inflammatory cytokines, and vasoconstricting mediators…

…coronary syndromes and recent myocardial infarction COLCOT The COLCOT trial enrolled 4745 patients within 30 days of myocardial infarction. Participants received colchicine 0.5 mg…

…As of March 25 (2020), there have been more than 530,000 individuals with confirmed COVID 19, of whom more than 33,000 have died…

…myositis, mixed connective tissue disease, Sjögren syndrome, SLE and APS. Some patient groups have a two to three fold greater prevalence of asymptomatic atherosclerotic cardiovascular…

…alone often fails to capture these specific pathological drivers. 5 Physiological Mechanisms of Cardioprotection: Direct vs. Weight Mediated The profound cardiovascular benefits observed with incretin…

…progressive, and highly complex lipid driven inflammatory disease of the arterial intima that serves as the fundamental pathophysiological substrate for acute coronary syndromes (ACS), including…