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🟠 Nitroprusside

…NO) that induces vasodilatation of both arterioles and veins via generation of cyclic GMP, which then activates calcium sensitive potassium channels in the cell membrane…

🟠 Nitroglycerin

…veins) via generation of cyclic GMP, which then activates calcium sensitive potassium channels in the cell membrane. Nitroglycerin is similar in action and pharmacokinetics to…

Adenosine: Administration Technique, Dose Escalation and Precautions

…In addition to these direct effects, adenosine antagonizes catecholamine stimulated adenylate cyclase. This inhibition decreases the accumulation of cyclic adenosine monophosphate (cAMP), which in turn…

Noradrenaline, Dobutamine and Levosimendan: Practical Infusion Use

Cardiology Critical care Pharmacology & dosing Definition and Pathophysiology In the management of acute heart failure and cardiogenic shock, intravenous vasoactive agents are categorised according to…

Cardiovascular Risk in Inflammatory and Autoimmune Disease

…prevalence of asymptomatic atherosclerotic cardiovascular disease (ASCVD) than the general population. The evidence for premature atherosclerosis is particularly strong in RA and SLE. Ankylosing spondylitis…

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