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Blood Pressure Targets in Older and Frail Adults

Cardiology Clinical medicine Definition and Clinical Context Blood pressure management in older adults must account for chronological age, biological age, frailty, multimorbidity, cognitive status, functional…

NSTEMI: Risk Stratification and Timing of the Invasive Strategy

…with the clinical context, the ECG, haemodynamic stability, and cardiac biomarker results. Patients with suspected ACS are categorized into a STEMI pathway or an NSTE…

Short Synacthen test

Procedurer The test measures the ability of the adrenal cortex to respond to maximal ACTH stimulation, and it is rarely the injection itself that determines…

Cardiac amyloidosis

…conditions Clinical Red Flags Raising Suspicion of Cardiac Amyloidosis Demographic and Clinical Context Cardiac amyloidosis should be suspected in patients older than 65 years presenting…

Pre-test Probability and Selection of Non-invasive Testing in Stable Angina

…context The assessment begins with the clinical presentation, including the character and stability of chest discomfort, associated dyspnoea, and the presence of risk factors or…

Atropine: Dosing in Bradycardia and Its Limitations

…context of acute coronary syndromes, particularly ST elevation myocardial infarction (STEMI), ischemic injury can disrupt the conduction system at any level, producing atrioventricular (AV) or…

Pulmonary Hypertension: Classification and Treatment Principles

…or a range of miscellaneous conditions. Because several mechanisms may coexist, diagnosis and classification must integrate haemodynamics with the patient’s clinical context and the…

Type 2 Myocardial Infarction: Mechanisms and Management

…may occur in the context of acute myocardial ischaemia, though abnormal cardiac troponin (cTn) values in the setting of acute or chronic heart failure are…

First-degree AV block (AV block I, AV block 1)

…also referred to as 1st degree AV block, AV block I, or AV block 1. Before proceeding, it is recommended to review the basic concepts…

Chronic Kidney Disease as a Cardiovascular Risk Factor

…stages: CKD stage eGFR Clinical context Cardiovascular or renal significance 1 60 mL/min/1.73 m² Abnormal urinalysis or renal imaging Risk of progression…

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