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Myocardial Mechanics: Structure and Function of Myocardial Fibers

Echocardiography Structure and contractile function of myocardial fibers The left ventricular wall can be subdivided into several layers. These layers are similar to those seen…

Relaxation of the left ventricle

…the aorta. Afterload affects myocardial muscle fibers during systole and diastole. Afterload is a function of the following three variables: Aortic resistance (pressure). Left ventricular…

Atrial and ventricular enlargement: hypertrophy and dilatation on ECG

…on the ECG as increased amplitudes of the QRS complexes. The explanation is straightforward: myocardial muscle mass is increased and therefore it generates greater electrical…

Cardiac electrophysiology and ECG interpretation

…of cardiac cells: Conduction cells form the fiber networks that sprout into the myocardium and disseminate the action potential. These cells have virtually no contractile…

Exercise physiology: from normal response to myocardial ischemia & chest pain

…of such changes is simply to enable the cardiopulmonary system to increase its delivery of oxygen to skeletal muscle and myocardium. The oxygen consumption – and…

ST-Elevation Myocardial Infarction Complicated by Cardiogenic Shock

…accounting for approximately 80% of cases. Other causes include acute mechanical complications—particularly ventricular septal defect (VSD) and papillary muscle rupture with acute severe mitral…

Strain, strain rate and speckle tracking: Myocardial deformation

…Figure 1A 2C. The orientation of myocardial muscle fibers results in longitudinal, radial and circumferential shortening (contraction). Traditional methods for investigating left ventricular function — e…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…and degradation. Histologically, a vulnerable plaque is defined by a fibrous cap thickness of less than 65 μm, heavy macrophage infiltration, sparse smooth muscle…

Aortic regurgitation

…function and the development of myocardial fibrosis. Contractile dysfunction further aggravates the regurgitation (the regurgitation volume increases). Mechanically, wall stress (the load on individual muscle…

Myocardial Injury Versus Infarction: Interpreting Troponin Elevation

…are components of the myocardial contractile apparatus and are expressed predominantly in cardiac muscle. Troponin I is highly specific for myocardial injury. Interpretation of troponin…

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