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Blood gas interpretation: quick reference for acid-base disorders

…is which change can explain the pH, and whether the other variable lies within the expected range of compensation. Sample type and baseline values An…

Arrhythmogenic Right Ventricular Cardiomyopathy / Dysplasia (ARVC, ARVD)

…with variable penetrance and expressivity. Recessive forms exist, although they are rare (Naxos disease, Carvajal syndrome). The prevalence of ARVC is between 0.02 and…

Differential Diagnosis of Chest Pain: A Clinical Overview

…can be highly variable, particularly in females, the elderly, or patients with diabetes [4]. Associated Findings: The sudden onset of symptoms coupled with diaphoresis should…

Heart Failure With Preserved Ejection Fraction: Diagnosis and Treatment

…contraction and relaxation. Structural and vascular consequences Common structural consequences include left ventricular hypertrophy, left atrial enlargement, and abnormalities of diastolic filling. Mitral regurgitation may…

Dilated Cardiomyopathy (DCM): Definition, Types, Diagnostics & Treatment

…with early onset of heart failure is common among these individuals. The majority of the mutations are inherited in an autosomal dominant manner with variable…

Brugada Syndrome: Diagnosis & SCD Prevention

…channelopathy with incomplete penetrance and variable expressivity. The first and most critical genetic locus identified was SCN5A , the gene encoding the alpha subunit of the…

🟠 HCM Risk-SCD Calculator

…takes into account the following variables: Maximum Left Ventricular Wall Thickness (MaxLVWT) : Hypertrophy is a hallmark of HCM and is associated with increased arrhythmic risk…

Chronotropic incompetence (inability to increase heart rate)

…of overall and cardiovascular mortality. The condition is very common among individuals with heart failure. Notably, beta blockers actually increase chronotropic competency in patients with…

Chronic Kidney Disease as a Cardiovascular Risk Factor

…Nephrology Definition and pathophysiology Chronic kidney disease (CKD) is defined by abnormalities of renal structure or function that persist for more than 3 months and…

Percutaneous Coronary Intervention for Chronic Total Occlusions: Indications and Outcomes

…and improvement of symptoms and quality of life. Restoration of patency may be particularly relevant when the occluded artery supplies viable myocardium with demonstrable ischaemia…

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