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Contrast-Associated Acute Kidney Injury: Risk Assessment and Prevention

…disease, particularly diabetic kidney disease and advanced CKD. The clinical course is often more rapidly reversible than that of other forms of acute tubular necrosis…

Short Synacthen test

…cortisol assay, whether the samples were taken at the right times, and whether you know which decision threshold your own laboratory's method uses. In…

ST-Elevation Myocardial Infarction: Diagnosis and Electrocardiographic Criteria

…angina pectoris. The location of the pain beneath the xiphoid and epigastrium, combined with patient denial, often leads to a mistaken impression of indigestion. STEMI…

Pulmonary Hypertension: Classification and Treatment Principles

…hypertension (CTEPH) and chronic thromboembolic pulmonary disease Group 5: PH with unclear or multifactorial mechanisms PAH is a distinct and uncommon form of precapillary PH…

Statin Intolerance and Statin-Associated Muscle Symptoms

…Complete intolerance is uncommon. Most patients who report intolerance can ultimately take some form of statin therapy after systematic reassessment and rechallenge. The principal manifestation…

Antianginal Therapy: Beta-Blockers, Calcium Channel Blockers, Nitrates, and Ranolazine

…uncomplicated acute coronary syndrome when LVEF is 40% is not definitive. Observational studies have yielded conflicting results, and the appropriate duration of therapy in p

Arrhythmogenic Right Ventricular Cardiomyopathy / Dysplasia (ARVC, ARVD)

…other ECG changes (see below) should lead to a suspicion of ARVC. The gradual loss of myocardium leads to ventricular dilation and right heart failure…

Immediate Management of Type A and Type B Aortic Dissection

…trauma Definition and Pathophysiology Aortic dissection is a major form of acute aortic syndrome (AAS), alongside intramural haematoma, penetrating atherosclerotic ulcer, aortic pseudoaneurysm and traumatic…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…than confined to a single lesion. Consequently, local revascularization must be accompanied by systemic treatment aimed at stabilizing the broader atherosclerotic disease. Pathophysiology Mechanisms of…

Atrial Flutter: Mechanisms, ECG Recognition and Management

…reentry. In the common form of typical atrial flutter, the reentrant circuit is confined to the right atrium and travels in a counterclockwise direction. The…

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