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Contrast-Associated Acute Kidney Injury: Risk Assessment and Prevention

…risk factors The principal determinant of risk is baseline renal function. The risk is increased by: CKD, especially advanced CKD; diabetic kidney disease; older age…

Statin Intolerance and Statin-Associated Muscle Symptoms

…Predisposing factors The likelihood of SAMS increases with higher statin doses and with several patient and treatment related factors: Age older than 80 years Female…

ST-Elevation Myocardial Infarction: Diagnosis and Electrocardiographic Criteria

…is not uniformly present. The proportion of painless or silent STEMIs is greater in patients with diabetes mellitus and increases with age. STEMI may present…

Pulmonary Hypertension: Classification and Treatment Principles

…PH) is a heterogeneous pathophysiological disorder characterized primarily by elevation of pulmonary arterial pressure. It may arise from pulmonary vascular disease, left sided cardiac disease…

Arrhythmogenic Right Ventricular Cardiomyopathy / Dysplasia (ARVC, ARVD)

…is confined to the left ventricle. ARVC causes ventricular tachycardia and sudden cardiac arrest; the disease is one of the most common causes of sudden…

Short Synacthen test

…the day of the test can therefore be given dexamethasone. That is the practical key: the patient does not have to be left unprotected for…

Antianginal Therapy: Beta-Blockers, Calcium Channel Blockers, Nitrates, and Ranolazine

…blood pressure, left ventricular dysfunction, contraindications, or intolerance limit escalation of beta blocker or CCB therapy. Nicorandil and trimetazidine are additional options in selected patients…

Immediate Management of Type A and Type B Aortic Dissection

Cardiology Emergency medicine Surgery & trauma Definition and Pathophysiology Aortic dissection is a major form of acute aortic syndrome (AAS), alongside intramural haematoma, penetrating atherosclerotic ulcer…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…than confined to a single lesion. Consequently, local revascularization must be accompanied by systemic treatment aimed at stabilizing the broader atherosclerotic disease. Pathophysiology Mechanisms of…

Atrial Flutter: Mechanisms, ECG Recognition and Management

…reentry. In the common form of typical atrial flutter, the reentrant circuit is confined to the right atrium and travels in a counterclockwise direction. The…

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