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Hypertension: Initial Combination Therapy and Drug Selection

…control and adherence, although prospective outcome trials have not directly established that upfront combination therapy is superior to upfront monotherapy for every patient with isolated…

🟠 Lipid lowering therapy after ACS

…statin therapy (Class I recommendation). • Immediate combination with ezetimibe can be considered if LDL C 3.5 mmol/L, possibly initiated during hospitalization (Class IIb…

🟠 Prasugrel (Effient, Efient, Prasita)

…active metabolite and increased bleeding risk compared to patients weighing ≥ 60 kg. Renal impairment No dose adjustment is required, including for patients with end stage…

Heart Failure With Mildly Reduced Ejection Fraction

Cardiology Definition and classification Heart failure with mildly reduced ejection fraction (HFmrEF) is a clinical syndrome defined by the combination of symptoms and/or signs…

Hypertensive crisis: drugs and doses

…the adverse effects and the important precautions. A hypertensive emergency is defined by a markedly raised blood pressure in combination with new or progressive acute…

🟠 Ticagrelor (Brilinta, Brilique)

…precautions, and other relevant information for the drug Ticagrelor . Table 1 Summary Indications Ticagrelor, in combination with acetylsalicylic acid (ASA), is indicated for the prevention…

Left Ventricular Thrombus After Myocardial Infarction

…particularly associated with extensive anterior or transmural infarction, apical dysfunction, LV aneurysm formation, and reduced LV systolic function. The principal mechanisms are the combination of…

Principles of myocardial perfusion imaging (SPECT, PET), coronary blood flow and flow reserve (CFR)

…and stress conditions. MPI uses radiotracers in combination with single photon emission computed tomography (SPECT) or positron emission tomography (PET) to assess myocardial perfusion and…

Sepsis and septic shock: quick reference for the first hour

…Older people, the immunosuppressed and patients with renal or hepatic failure can have subtle symptoms. Findings that suggest acute organ dysfunction Organ or system Finding…

Antianginal Therapy: Beta-Blockers, Calcium Channel Blockers, Nitrates, and Ranolazine

…and combinations are frequently required. The central therapeutic aim is symptom control rather than modification of long term cardiovascular outcomes. With the important exception of…

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