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Sepsis and septic shock: quick reference for the first hour

…This combination carries a high mortality [1,2]. Give antibiotics immediately and aim for administration within one hour in septic shock, or when sepsis is…

Upper gastrointestinal bleeding: quick reference

…tachycardia a cold periphery and delayed capillary refill confusion, drowsiness or syncope oliguria a rising lactate or metabolic acidosis repeated fresh haematemesis haematochezia in combination…

Hypertension: Initial Combination Therapy and Drug Selection

…more than one pathophysiological pathway, combinations generally lower blood pressure more effectively than simply increasing the dose of a single drug. They may also permit…

🟠 Lipid lowering therapy after ACS

…C ≥ 1.4 mmol/L (55 mg/dL): • Add ezetimibe (if not already added earlier). • Add a PCSK9 inhibitor (if statin + ezetimibe combination is insufficient).

🟠 Prasugrel (Effient, Efient, Prasita)

…a 60 mg loading dose on an empty stomach may provide the fastest onset of effect. Do not crush or split the tablet . Warnings and…

Heart Failure With Mildly Reduced Ejection Fraction

…ejection fraction (HFmrEF) is a clinical syndrome defined by the combination of symptoms and/or signs of heart failure and a left ventricular ejection fraction …

Hypertensive crisis: drugs and doses

…the adverse effects and the important precautions. A hypertensive emergency is defined by a markedly raised blood pressure in combination with new or progressive acute…

🟠 Ticagrelor (Brilinta, Brilique)

…in combination with acetylsalicylic acid (ASA), is indicated for the prevention of atherothrombotic events in adult patients with acute coronary syndrome (ACS) or a prior…

Left Ventricular Thrombus After Myocardial Infarction

…and closely adherent to the endocardial surface. Protruding or mobile: extending into the ventricular cavity, sometimes with independently mobile components. Although a mural thrombus is…

Principles of myocardial perfusion imaging (SPECT, PET), coronary blood flow and flow reserve (CFR)

…and numerical insights into myocardial blood flow under rest and stress conditions. MPI uses radiotracers in combination with single photon emission computed tomography (SPECT) or…

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