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Lipid-Lowering Therapy: Statins as First-Line Treatment

…reduces thrombogenicity, and favourably modifies inflammatory and collagen related components of atherosclerotic plaque. These effects help explain why reductions in cardiovascular events are substantially greater…

ST-Elevation Myocardial Infarction: Diagnosis and Electrocardiographic Criteria

…coronary occlusion. Plaque rupture typically involves a thin, collagen poor fibrous cap overlying a large lipid core with many macrophages, resulting in a red, fibrin…

Non-ST Elevation Acute Myocardial Infarction (NSTEMI) and Unstable Angina

…often presenting clinically as Non ST Elevation Myocardial Infarction (NSTEMI) rather than STEMI [4] . Calcified Nodules: A less common mechanism (2 5%), characterized by eruptive…

Pericardial Effusion & Cardiac tamponade

…vessels. The visceral layer consists of mesothelian cells, collagen and elastin and is fused with the myocardium. At the departures of the larger vessels, the…

Sinus node dysfunction (SND) and sick sinus syndrome (SSS)

…degenerative disease (fibrosis) Myocardial ischemia/infarction Lesions due to heart surgery Myocarditis Collagen disease Amyloidosis Risk of supraventricular tachyarrhythmia (tachycardia) Sinus node dysfunction is also…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…into characteristic foam cells. The accumulation of these foam cells forms the earliest macroscopically visible lesion of atherosclerosis: the fatty streak [5] . Ruptured atherosclerotic lesion…

Nonspecific intraventricular conduction delay (defect)

…causes of nonspecific intraventricular conduction delay According to the American Heart Association/American College of Cardiology and the Heart Rhythm Society (AHA/ACCF/HRS) recommendations…

🟠 HCM Risk-SCD Calculator

…ICD) is warranted. The HCM Risk SCD calculator is validated to estimate the 5 year risk of SCD in patients with HCM. What is the…

Fourth Universal Definition of Myocardial Infarction: Types 1–5

…advent of highly sensitive cardiac biomarkers, the European Society of Cardiology (ESC), American College of Cardiology (ACC), American Heart Association (AHA), and World Heart Federation …

Myocardial ischemia and infarction: lack of oxygen or imbalance between supply/demand

…myoardial infarction. An important discovery was reported in 1930 when Buchner and colleages showed that myocardial contractility was closely related to myocardial blood flow. This…

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