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Lipid-Lowering Therapy: Statins as First-Line Treatment

…mortality in patients with coronary artery disease irrespective of the baseline cholesterol concentration. Intensive statin treatment is more effective than moderate intensity treatment in reducing…

ST-Elevation Myocardial Infarction: Diagnosis and Electrocardiographic Criteria

…occasionally be reported as stabbing or burning. It resembles the discomfort of angina pectoris but typically occurs at rest, is more severe, and lasts longer…

Non-ST Elevation Acute Myocardial Infarction (NSTEMI) and Unstable Angina

…and a highly inflamed fibrous cap measuring less than 65 micrometers in thickness. Macrophage derived matrix metalloproteinases (MMPs) degrade the interstitial collagen of the cap…

Pericardial Effusion & Cardiac tamponade

…fluid in the pericardial cavity exceeds 50 mL, there is an effusion, which is considered pathological. The effusion, as a rule, is ecolucent (ecofatical), but…

Sinus node dysfunction (SND) and sick sinus syndrome (SSS)

…The conditions encircled by the term sinus node dysfunction are as follows: Sinus bradycardia (which in its purest form means that the automaticity is diminished)…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…switch from a contractile to a synthetic state, producing abundant extracellular matrix (ECM) components, primarily interstitial collagen types I and III, elastin, and proteoglycans [6] …

Nonspecific intraventricular conduction delay (defect)

…greater than 110 ms in adults, greater than 90 ms in children 8 to 16 years of age, and greater than 80 ms in children…

🟠 HCM Risk-SCD Calculator

…widely used in clinical practice and is endorsed by major cardiology guidelines, including those from the European Society of Cardiology (ESC), American College of Cardiology…

Fourth Universal Definition of Myocardial Infarction: Types 1–5

…the past century. Initial post mortem observations in the late 19th century first linked thrombotic occlusion of a coronary artery with myocardial necrosis. Although early…

Myocardial ischemia and infarction: lack of oxygen or imbalance between supply/demand

…reduce infarct size, which is generally attributed to its reduction of heart rate and contractility. But as it turns out, [2] the reduction in heart…

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