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Acute Aortic Syndromes: Intramural Haematoma and Penetrating Atherosclerotic Ulcer

Cardiology Emergency medicine Definition and Pathophysiology Acute aortic syndromes comprise classic aortic dissection, intramural haematoma (IMH), and penetrating atherosclerotic ulcer (PAU). Aortic dissection accounts for…

Immediate Management of Type A and Type B Aortic Dissection

…penetrating atherosclerotic ulcer, aortic pseudoaneurysm and traumatic aortic injury. In classic dissection, an intimal tear permits blood to enter the diseased aortic media. Blood then…

Left Bundle Branch Block: ECG criteria and clinical implications

…The diagnostic requirements for LBBB vary by the stringency of the criteria applied: Classic Criteria : These include a QRS duration of $\ge 120$ msec…

ACE Inhibitor Cough and Angioedema: Practical Management

…inhibitor therapy is bradykinin mediated rather than mast cell mediated, distinguishing it from classic allergic reactions. Clinical Presentation and Symptoms ACE Inhibitor Induced Cough ACE…

Acute Limb Ischaemia: Recognition and Urgent Management

…an hour of arterial occlusion. The classic clinical constellation is remembered as the “six Ps”: Pain Paresthesia Pallor Pulselessness Poikilothermia, or coldness Paralysis Pain is…

Differential Diagnosis of Chest Pain: A Clinical Overview

…cardiovascular cause [4]. 2. Aortic Dissection Pain Characteristics: The classic symptom is a severe, often sharp pain that characteristically radiates to the back [5]. 3…

A New Approach to Acute Coronary Syndromes: Occlusion MI (OMI) vs. Non-Occlusion MI (NOMI)

…artery occlusion causing transmural ischemia and requiring urgent reperfusion, even in the absence of classic ST elevation. Multiple studies have demonstrated the superior sensitivity of…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…receptors (e.g., SR A, CD36) that, unlike the classic LDL receptor, are not downregulated by intracellular cholesterol accumulation. Consequently, macrophages indiscriminately phagocytose oxLDL until…

Acute coronary syndrome: quick reference for loading doses and time targets

…STEMI criteria and occlusion patterns on the ECG Classic ST elevation criteria New ST elevation at the J point in at least two anatomically contiguous…

Peripheral Artery Disease: Diagnosis, Ankle–Brachial Index and Risk Management

…slow gait without describing classic claudication. In older adults, approximately 40% are asymptomatic, 50% report atypical leg symptoms and fewer than 10% have classic claudication…

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