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Pulmonary Hypertension: Classification and Treatment Principles

…most common risk factor for PH. It produces postcapillary PH through elevation of left atrial and pulmonary venous pressure. In some patients, chronic postcapillary pr

Chronic Kidney Disease as a Cardiovascular Risk Factor

Cardiology Nephrology Definition and pathophysiology Chronic kidney disease (CKD) is defined by abnormalities of renal structure or function that persist for more than 3 months…

Obesity and Cardiovascular Disease: Assessment and Treatment

…diabetes mellitus Atherosclerotic cardiovascular events HF and atrial fibrillation Obesity therefore acts both as an independent cardiovascular risk factor and as a driver of hypertension…

Refractory Angina: Options When Standard Therapy Fails

…ischaemia without an obstructive epicardial lesion. Once conventional anti ischaemic targets have been exhausted, proposed therapeutic approaches act through several broad mechanisms: Promotion of coronary…

Post-Infarction Mechanical Complications: Ventricular Septal, Free-Wall, and Papillary Muscle Rupture

…Female sex. Hypertension. Absence of an adequate collateral circulation. A first or anterior infarction. Single vessel disease without collateral support. Chronic kidney disease, particularly in…

Inotropes and vasopressors: doses, indications, contraindications and effects

…a central venous catheter and an arterial line is necessary to achieve an optimal result. Overview of vasopressors and inotropes Vasoconstriction Vasodilatation Positive inotropy Phenylephrine…

Heart Failure With Preserved Ejection Fraction: Diagnosis and Treatment

…Increasing severity of mitral regurgitation is associated with worse outcomes. Pulmonary hypertension secondary to left heart disease may occur because elevated left sided filling pressures…

Cardiac thromboembolism: cardiac sources of embolism

…Ischemic heart disease Both acute and chronic ischemic heart disease (including complications) can cause embolisms. Left ventricular aneurysm with thrombus Cardiomyopathies Valve prosthesis Devices (pacemaker…

Levosimendan (Simdax, Simendan) in acute heart failure

…of Cardiogenic Shock. N Engl J Med 2021; 385:516 525 Indications Severe left ventricular failure, acute or chronic. Severe biventricular failure, acute or chronic…

Cardiac arrest due to electrolyte imbalance

…etiologies when promptly and appropriately addressed. Both venous and arterial blood gases can be utilized for the analysis of electrolyte levels. Electrocardiography (ECG) serves as…

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