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Pulmonary Hypertension: Classification and Treatment Principles

…most common risk factor for PH. It produces postcapillary PH through elevation of left atrial and pulmonary venous pressure. In some patients, chronic postcapillary pr

Chronic Kidney Disease as a Cardiovascular Risk Factor

…cardiac and renal axes may produce cardiorenal syndrome. Worsening renal function in the presence of persistent congestion is particularly associated with elevated central venous pressure…

Obesity and Cardiovascular Disease: Assessment and Treatment

…factor and as a driver of hypertension, diabetes, dyslipidaemia and systemic inflammation. It is also associated with respiratory disorders, notably obstructive sleep apnoea (OSA) and…

Refractory Angina: Options When Standard Therapy Fails

…of a chronic total coronary occlusion. Angina or ischaemia with non obstructive coronary arteries (ANOCA/INOCA), after appropriate investigation has identified the relevant endotype and…

Post-Infarction Mechanical Complications: Ventricular Septal, Free-Wall, and Papillary Muscle Rupture

…Clinical presentation and symptoms A new episode of hypotension, recurrent chest pain, pulmonary congestion, a new cardiac murmur, or jugular venous distension in the days…

Inotropes and vasopressors: doses, indications, contraindications and effects

…electrocardiographic and haemodynamic monitoring with ECG, a central venous catheter and an arterial line is necessary to achieve an optimal result. Overview of vasopressors and…

Heart Failure With Preserved Ejection Fraction: Diagnosis and Treatment

…by symptoms and/or signs of HF with LVEF 41–49%. In this group, structural abnormalities such as left atrial enlargement or left ventricular hypertrophy…

Cardiac thromboembolism: cardiac sources of embolism

…atrial fibrillation and atrial flutter. Ischemic heart disease Both acute and chronic ischemic heart disease (including complications) can cause embolisms. Left ventricular aneurysm with thrombus…

Levosimendan (Simdax, Simendan) in acute heart failure

…Compared with Dobutamine in the Treatment of Cardiogenic Shock. N Engl J Med 2021; 385:516 525 Indications Severe left ventricular failure, acute or chronic…

Cardiac arrest due to electrolyte imbalance

…Hypotension Arrhythmias and ECG changes Cardiac arrest Treatment Furosemide 1 mg/kg IV. Hydrocortisone 300 mg IV. Pamidronate 30 90 mg IV. Causal treatment of…

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