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Chronic Coronary Syndrome: Diagnosis and Initial Evaluation

…state. Patients may remain stable for prolonged periods, but chronic coronary disease can progress or destabilize abruptly, leading to an acute coronary syndrome (ACS). Clinical…

Chronic Kidney Disease as a Cardiovascular Risk Factor

…ratio (UACR) above 30 mg/g—or both. The eGFR is generally estimated from serum creatinine using the Chronic Kidney Disease Epidemiology Collaboration (CKD EPI…

Chronic Heart Failure With Reduced Ejection Fraction: Four-Pillar Therapy

…to fluid retention and worsening congestion The clinical course may be chronic and relatively stable or punctuated by episodes of worsening heart failure requiring hospitalization…

Percutaneous Coronary Intervention for Chronic Total Occlusions: Indications and Outcomes

…When clinically significant, it may present with chronic angina, an anginal equivalent or exertional dyspnoea. Patients may continue to have lifestyle limiting symptoms despite guideline…

Pre-test Probability and Selection of Non-invasive Testing in Stable Angina

…occur at a low level of exertion, or are associated with high event risk. The apparent differences between thresholds reflect different guideline frameworks and clinical…

Preeclampsia and Hypertensive Pregnancy Disorders as Future Cardiovascular Risk

Cardiology Clinical medicine Definition and clinical classification Hypertensive disorders of pregnancy comprise chronic or pre existing hypertension, gestational hypertension, and preeclampsia. Collectively, they affect approximately…

Causes of sudden cardiac arrest

…commonly stated that approximately 80% of all cardiac arrests are caused by acute or chronic coronary artery disease, with the latter being the most common…

Obesity and Cardiovascular Disease: Assessment and Treatment

…patients with HFpEF can have pathophysiological characteristics that differ from those of non obese patients, and obesity complicates assessment of intravascular volume in both ambulatory…

Arrhythmias before and during cardiac arrest

…is not an absolute rule. While it often holds true for cardiac arrests caused by chronic or acute ischemic heart disease, it is often not…

Refractory Angina: Options When Standard Therapy Fails

…of patients with CAD. The pathophysiology of refractory angina is heterogeneous. In obstructive CAD, symptoms may result from extensive or diffuse epicardial disease, chronic total…

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