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Chronic Coronary Syndrome: Diagnosis and Initial Evaluation

Cardiology Myocardial ischemia and infarction Definition and Pathophysiology Chronic coronary syndromes (CCS) comprise the clinical manifestations of chronic structural and/or functional disease involving the…

Chronic Heart Failure With Reduced Ejection Fraction: Four-Pillar Therapy

…and improve symptoms, functional capacity and quality of life. The underlying aetiology is heterogeneous. Chronic heart failure evaluation should therefore seek reversible or treatable causes…

Chronic Kidney Disease as a Cardiovascular Risk Factor

…Definition and pathophysiology Chronic kidney disease (CKD) is defined by abnormalities of renal structure or function that persist for more than 3 months and have…

Percutaneous Coronary Intervention for Chronic Total Occlusions: Indications and Outcomes

Myocardial ischemia and infarction Definition and pathophysiology A chronic total occlusion (CTO) is a complete or nearly complete coronary arterial obstruction that has persisted for…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

Cardiology Coronary Atherosclerosis Coronary atherosclerosis is a chronic, progressive, and highly complex lipid driven inflammatory disease of the arterial intima that serves as the fundamental…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

…is a chronic, inflammatory disease of the arterial wall in which lipid accumulation, vascular cell dysfunction, immune cell recruitment, extracellular matrix remodelling, and thrombosis interact…

Obesity and Cardiovascular Disease: Assessment and Treatment

Cardiology Endocrinology & metabolism Definition and pathophysiology Obesity is a chronic, relapsing and biologically complex disease characterized by excessive accumulation of adipose tissue. It is an…

Coronary Artery Disease

…artery disease Chronic coronary syndromes (CCS) Stable coronary artery disease (CAD), frequently referred to as stable angina pectoris , has traditionally been defined and managed as…

Non-ST Elevation Acute Myocardial Infarction (NSTEMI) and Unstable Angina

…Plaques, Atherothrombosis Coronary atherosclerosis is a chronic, progressive, and highly dynamic inflammatory disease of the arterial wall. It is characterized by the subendothelial accumulation of…

Stable Coronary Artery Disease (Angina Pectoris): Diagnosis, Evaluation, Management

…artery disease Chronic coronary syndrome (CCS) Stable coronary artery disease (CAD), frequently referred to as stable angina pectoris , has traditionally been defined and managed as…

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