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Hypertensive crisis: quick reference for acute blood pressure lowering

…up. Rapid lowering can worsen cerebral, coronary and renal perfusion, particularly in patients with long standing hypertension and a rightward shifted autoregulation [1,3]. The…

Inotropes and vasopressors: doses, indications, contraindications and effects

…vasodilatation in the coronary, renal, cerebral and mesenteric vessels. Few Dopamine — intermediate dose Cardiogenic shock. Vasodilatory shock. Heart failure, acute or chronic. Bradycardia (second line…

Cardiac thromboembolism: cardiac sources of embolism

…with cerebral atherosclerosis. Cryptogenic stroke : These cases have no known mechanism. Paradoxical embolism : Paradoxical embolism occurs when thromboembolic material is transported from the venous circulation…

Traumatic cardiac arrest

…include cerebral, facial, airway and thoracic injuries. Tension pneumothorax : Tension pneumothorax increases intrathoracic pressure, which subsequently compresses larger thoracic veins and thus inhibits venous return…

The physiology of cardiopulmonary resuscitation (CPR)

…decompressions that result in perfusion of cardiac, cerebral, and pulmonary tissue. Chest compressions produce perfusion of vital organs by increasing the pressure in the atria…

Assessment of the pupillary reflex in cardiac arrest

…result, pupils often dilate widely within 30–120 seconds of cardiac arrest and light reactivity is lost when cerebral blood flow ceases. In other words…

Short and long-term prognostication in cardiac arrest

…and anoxia ( Casas et al ). In cardiac arrest without chest compressions (i.e. if cerebral perfusion ceases), irreversible neuronal cell death starts within 5–6…

Hyponatraemia: quick reference for work-up and correction

…is to relieve the cerebral oedema quickly, not to normalise the plasma sodium. Chronic or minimally symptomatic hyponatraemia must be corrected in a controlled fashion…

Carotid Artery Disease: Screening, Medical Therapy and Revascularisation

…cerebral ischaemia; known CAD, PAD, or other atherosclerotic disease; diabetes and other cardiovascular risk factors; smoking, hypertension, hypercholesterolaemia, and sedentary behaviour; family history, particularly in…

Hypertensive crisis: drugs and doses

…a universal target. Chronic hypertension shifts autoregulation in the brain and kidneys towards higher pressures. Too rapid a normalisation can therefore cause cerebral, coronary or…

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