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Percutaneous Coronary Intervention for Chronic Total Occlusions: Indications and Outcomes

…Additional features associated with greater difficulty include a previously failed attempt, a blunt proximal stump, vessel bending, calcification and an occlusion length of at least…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…and spotty calcification. However, the concept has important limitations. Although thin capped fibroatheromas may have imaging characteristics associated with rupture, fewer than 5% of such…

Coronary Anatomy and Segmental Classification for the Clinician

…malignant than anomalous origin of the right coronary artery. High risk anatomical features include: An interarterial course between the aorta and pulmonary artery A slit…

Metabolic Syndrome: Definition and Clinical Significance

…related to insulin resistance and the risk of diabetes and cardiovascular disease than total adiposity alone. The waist circumference associated with risk varies among populations…

In-Stent Restenosis: Mechanisms and Treatment

…Factors associated with restenosis The risk of restenosis after metallic stent implantation is increased by: Small reference vessel size A small post procedural luminal diameter…

Complications of Coronary Angiography and Vascular Access Management

…is associated with fewer vascular and bleeding complications than femoral access. In patients with acute coronary syndrome, randomized evidence has demonstrated lower rates of access…

Coronary CT Angiography and CAD-RADS Reporting

…65 years and in patients with a lower suspicion of obstructive disease. Patients with no plaque or stenosis on CCTA should be reassured, and non…

Type 2 Diabetes and Cardiovascular Risk Management

…vascular and metabolic abnormalities. Diabetes is associated with inflammation, thrombosis and accelerated atherosclerosis. In CKD, additional mechanisms include vascular stiffness and accelerated medial calcification related…

Pre-test Probability and Selection of Non-invasive Testing in Stable Angina

…with the clinical presentation, including the character and stability of chest discomfort, associated dyspnoea, and the presence of risk factors or previously identified coronary calcification…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

…abundant foam cells and macrophages; a thin fibrous cap; positive remodelling; neovascularization; intraplaque haemorrhage; adventitial inflammation; spotty calcification. Nevertheless, the presence of these features does…

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