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Percutaneous Coronary Intervention for Chronic Total Occlusions: Indications and Outcomes

…Additional features associated with greater difficulty include a previously failed attempt, a blunt proximal stump, vessel bending, calcification and an occlusion length of at least…

Vulnerable Plaque and Mechanisms of Acute Coronary Occlusion

…and spotty calcification. However, the concept has important limitations. Although thin capped fibroatheromas may have imaging characteristics associated with rupture, fewer than 5% of such…

Coronary Anatomy and Segmental Classification for the Clinician

…proportion of sudden cardiac death in young athletes. Clinically, they may be categorized according to whether they are: Not associated with ischaemia Associated with episodic…

Metabolic Syndrome: Definition and Clinical Significance

…related to insulin resistance and the risk of diabetes and cardiovascular disease than total adiposity alone. The waist circumference associated with risk varies among populations…

In-Stent Restenosis: Mechanisms and Treatment

…Factors associated with restenosis The risk of restenosis after metallic stent implantation is increased by: Small reference vessel size A small post procedural luminal diameter…

Complications of Coronary Angiography and Vascular Access Management

…demonstrated lower rates of access site bleeding, surgical repair, and blood transfusion with radial access. Radial access has also been associated with lower overall major…

Coronary CT Angiography and CAD-RADS Reporting

…inconclusive. The principal diagnostic strength of CCTA is its ability to exclude significant anatomical CAD with high sensitivity and a high negative predictive value, particularly…

Type 2 Diabetes and Cardiovascular Risk Management

…been associated with reduced AF symptoms and better maintenance of sinus rhythm in cohort studies. Obesity, reduced exercise capacity, hypertension and dyslipidaemia commonly coexist and…

Pre-test Probability and Selection of Non-invasive Testing in Stable Angina

…with the clinical presentation, including the character and stability of chest discomfort, associated dyspnoea, and the presence of risk factors or previously identified coronary calcification…

Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

…abundant foam cells and macrophages; a thin fibrous cap; positive remodelling; neovascularization; intraplaque haemorrhage; adventitial inflammation; spotty calcification. Nevertheless, the presence of these features does…

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