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Antianginal Therapy: Beta-Blockers, Calcium Channel Blockers, Nitrates, and Ranolazine

…of long term cardiovascular outcomes. With the important exception of beta blockers in selected patients after acute myocardial infarction (MI), antianginal drugs have not been…

ECG changes caused by antiarrhythmic drugs, beta blockers & calcium channel blockers

…and electrolyte imbalance ECG The effect of antiarrhythmic drugs, beta blockers and calcium channel blockers on rhythm, conduction and ECG waveforms Although the purpose of…

Sotalol: Initiation, QT Monitoring and Renal Dosing

Arrhythmias and arrhythmology Pharmacology & dosing Definition and Pathophysiology Sotalol is a nonselective beta adrenoceptor blocker devoid of intrinsic sympathomimetic activity that also prolongs cardiac repolarization…

Sudden cardiac arrest: Case 3

…Male Age : 62 years History : Coronary bypass grafting; history of arrhythmias. Medications : beta blockers ECG 1 . Sinus rhythm interrupted by ventricular tachycardia (VT). ECG 3 …

🟠 Labetalol

…Postoperative hypertension. Mechanism of action Combined beta adrenergic and alpha adrenergic blocker with rapid onset of action. Labetalol has less antihypertensive efficacy as compared with…

🟠 Metoprolol

…Toprol ®, Seloken ® Indications Mycoardial ischemia. Perioperative hypertension. Mechanism of action Beta 1 adrenergic blocker. Effects Lowers blood pressure, reduces heart rate, myocardial oxygen…

🟠 Esmolol

…Relatively cardioselective (beta 1 receptor blocker) beta blocker with ultra short acting effect. • Half life: 9 minutes. Effects • Esmolol is a beta adrenergic receptor blocker…

🟠 Hydralazine

…No effect on venous circulation. • May cause reflex sympathetic stimulation (can be counteracted with simultaneous administration of beta blockers). Effects Induces arteriolar vasodilation without effects…

Chronotropic incompetence (inability to increase heart rate)

…individuals with heart failure. Notably, beta blockers actually increase chronotropic competency in patients with heart failure, despite their negative chronotropic effect. Among persons who do…

Levosimendan (Simdax, Simendan) in acute heart failure

…without increasing myocardial oxygen consumption. The inotropic effect of levosimendan is not affected by the concurrent use of beta blockers. The vasodilating effect reduces preload…

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