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Bempedoic Acid: Evidence and Clinical Use

…regulates substrates involved in lipid metabolism and inflammatory signalling. ACLY additionally influences fatty acid synthesis and may affect epigenetic regulation through changes in DNA acetylation…

Overview of the ECG Waves, Deflections, Intervals, Durations

…durations and assessment of rhythm is fundamental to ECG interpretation. Below follows a brief summary of the ECG waves, their appearance, terminology, physiological background and…

ST-Segment Elevation Myocardial Infarction: Diagnosis and ECG Criteria

…by inflammation, plaque morphology and location, comorbidities, environmental factors and genetic background. Thrombotic susceptibility is likewise affected by inflammation and other systemic influences. The severity…

PCSK9 Inhibitors: Indications, Efficacy and Access

…and prevent its interaction with the hepatic LDL receptor. They lower LDL C by approximately 50–60%, including in patients receiving background statin therapy and…

Interpretation of myocardial perfusion images (Myocardial SPECT / PET)

…Perfusion defects are further classified based on the intensity of tracer uptake and associated myocardial changes: Mild defects : Characterized by decreased tracer counts while preserving…

Introduction to cardiac arrest

…patient background, and the decision to initiate CPR is often ambiguous. Since the risk of attempting CPR is extremely low and the potentially catastrophic consequences…

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