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Atherosclerosis: Pathogenesis from Fatty Streak to Plaque Rupture

Cardiology Myocardial ischemia and infarction Definition and pathophysiology Atherosclerosis is a chronic, inflammatory disease of the arterial wall in which lipid accumulation, vascular cell dysfunction…

Complications of Coronary Angiography and Vascular Access Management

…been identified as important risk factors. Severe atherosclerosis of the axillary or subclavian arteries may increase the risk of embolization. Risk assessment should be individualized…

Cardiac thromboembolism: cardiac sources of embolism

…Left ventricular aneurysm with thrombus Cardiomyopathies Valve prosthesis Devices (pacemaker, ICD CRT) Endocarditis Cardiac tumors Atherosclerosis of the aorta LOW EMBOLIC POTENTIAL SEP (Spontaneous Echocardiographic…

ST-Elevation Myocardial Infarction (STEMI): Pathophysiology, Diagnosis, and Management

…of inert cholesterol debris, modern vascular biology has redefined atherosclerosis as a dynamic, immune mediated fibroproliferative response to endothelial injury [2] . The process initiates with…

Non-ST Elevation Acute Myocardial Infarction (NSTEMI) and Unstable Angina

…coronary atherosclerosis. The transition from a quiescent plaque to a highly thrombogenic surface occurs via three primary mechanisms: Plaque Rupture: Accounting for 60 70% of…

Coronary Artery Disease

…and size of atherosclerotic plaques. Typically, the first manifestation of coronary artery disease is stable angina, defined by exercise related chest pain. Patients with stable…

Stable Coronary Artery Disease (Angina Pectoris): Diagnosis, Evaluation, Management

…and size of atherosclerotic plaques. Typically, the first manifestation of coronary artery disease is stable angina, defined by exercise related chest pain. Patients with stable…

Carotid Artery Disease: Screening, Medical Therapy and Revascularisation

…Carotid disease therefore commonly coexists with coronary artery disease (CAD), peripheral artery disease (PAD), and other manifestations of systemic atherosclerosis. The principal clinical concern is…

Colchicine and Anti-inflammatory Therapy in Coronary Disease

…Patients with stable or chronic atherosclerotic coronary disease, many of whom have a previous acute coronary syndrome. The available evidence supports consideration of low dose…

Coronary Anatomy and Segmental Classification for the Clinician

…decision making increasingly combines anatomical imaging with functional assessment. A central practical principle is that the visual severity of a stenosis does not reliably establish…

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