…heparin, dalteparin is eliminated renally, so at eGFR below 30 ml/min the effect accumulates and the dose must be adjusted or the drug changed.

…intensity statin with a long half-life, allowing it to be taken at any time of day unlike simvastatin. Muscle complaints are frequently reported but…

…at doses well below the antidepressant range. The effect on pain occurs already at 10–50 mg and depends on noradrenergic and sodium-channel-mediated…

…response curve for blood pressure flattens already at 2,5 mg, while the adverse effect curves for potassium, sodium, urate, and glucose continue to rise —…

…and heart failure resembles that of selective COX-2 inhibitors and is seen already at doses below 100 mg/day and with short treatment duration…

…the pump and not vascular tone. Strong β₁ effect with marked β₂ effect means that stroke volume increases while systemic vascular resistance falls at low…

…Escitalopram Accord Selective serotonin reuptake inhibitor (SSRI) The most selective of the SSRIs and one of the best tolerated for depression and generalised anxiety disorder…

…in the loop of Henle. The dose–response relationship is a threshold curve, not a line: below the threshold nothing happens, and in renal failure…

…and the one with the least cardiovascular risk at a low dose. A short half-life of around 2 hours means the effect arrives and…

…never lets go. The effect is immediate and complete: unbound dabigatran in plasma falls by over 99 per cent directly after the infusion. The specificity…

…är att återställa andningen, inte vakenheten — därför titreras små doser, 0,04–0,4 mg åt gången, tills patienten andas tillräckligt. Den korta halveringstiden är…

…necessary at short notice. The disadvantages are continuous infusion, an unpredictable dose–response relationship due to binding to plasma proteins, and the risk of heparin…

…to 20 mmol per hour, and at most 40 mmol per hour in life-threatening hypokalaemia under continuous ECG monitoring. Hypokalaemia that refuses to rise…